Ossa J E, Alexander J, Schurig G G
Avian Dis. 1983 Oct-Dec;27(4):1106-11.
Hemorrhagic diarrhea, gross hemorrhagic enteritis, and death caused by intravenous virus injection of hemorrhagic enteritis virus (HEV) were prevented in otherwise susceptible turkey poults by surgical splenectomy. The splenectomized poults produced anti-HEV antibodies, which indicated that splenectomy did not completely prevent replication of the virus. These results indicate that the spleen is necessary for the development of the intestinal lesions of this disease. The role of a toxic factor in this disease is discussed.
通过手术切除脾脏，可预防原本易感的小火鸡因静脉注射出血性肠炎病毒（HEV）而引发的出血性腹泻、严重出血性肠炎及死亡。脾切除的小火鸡产生了抗HEV抗体，这表明脾切除并未完全阻止病毒复制。这些结果表明，脾脏对于该疾病肠道病变的发展是必要的。本文还讨论了毒性因子在该疾病中的作用。
