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孕妇中抗巨细胞病毒的ELISA抗体:自然流产中的患病率及其相关性

ELISA antibodies to cytomegalovirus in pregnant patients: prevalence in and correlation with spontaneous abortion.

作者信息

Luerti M, Santini A, Bernini O, Castiglioni M, Ragni M C

出版信息

Biol Res Pregnancy Perinatol. 1983;4(4):181-3.

PMID:6317066
Abstract

Prevalence of seroimmunity to cytomegalovirus (CMV) infection was tested by detecting ELISA IgG antibodies in 230 pregnant subjects from low socioeconomic backgrounds. Seroimmunity increased from 64.3% to 92.0% between the ages 15-20 and 35-40. Furthermore, ELISA IgM antibodies were detected during hospitalization in a group of 56 women whose pregnancies ended in spontaneous abortion and in a paired matched-control group. The overall percentage of IgM-positive reactions was 5.35% in the group with abortion. The percentage for only second trimester abortions amounted to 18.75%. There was no IgM-positive reaction in the control group.

摘要

通过检测230名来自社会经济背景较低的孕妇的ELISA IgG抗体,来测试巨细胞病毒(CMV)感染的血清免疫流行率。血清免疫在15至20岁和35至40岁之间从64.3%升至92.0%。此外,在一组56名妊娠以自然流产告终的妇女及其配对的匹配对照组住院期间检测了ELISA IgM抗体。流产组中IgM阳性反应的总体百分比为5.35%。仅孕中期流产的百分比达18.75%。对照组中没有IgM阳性反应。

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Biol Res Pregnancy Perinatol. 1983;4(4):181-3.
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