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[一种新型超低剂量复方避孕药的临床应用]

[Clinical aspects of a new, very low dose combination contraceptive].

作者信息

Mladenović D, Grcić R, Pestelek B, Kapor M

出版信息

Fortschr Med. 1978 Apr 6;96(13):723-6.

PMID:631715
Abstract

In a multicentre trial in Yugoslavia 150 fertile women were treated during 2541 menstrual cycles with Ovoresta M, a new low-dosed combined oral contraceptive pill. Each tablet contains 0.75 mg lynestrenol and 0.0375 mg ethinyloestradiol. Evaluation of the results shows that there were no pregnancies. Irregular bleedings occurred in 8.1% of all cycles. The side effects recorded were mainly due to the fact that for 140 of the 150 participants this was the first oral contraceptive they ever used. 2 women dropped out for relevant reasons (irregular bleedings). Because of the low dosage of active ingredients the authors consider Ovoresta M a welcome supplement to the existing oral contraceptives.

摘要

在南斯拉夫进行的一项多中心试验中,150名育龄妇女在2541个月经周期内使用了新型低剂量复方口服避孕药Ovoresta M进行治疗。每片药含有0.75毫克炔诺孕酮和0.0375毫克炔雌醇。结果评估显示没有怀孕情况发生。在所有周期中,8.1%出现了不规则出血。记录的副作用主要是因为150名参与者中有140人是首次使用口服避孕药。2名女性因相关原因(不规则出血)退出。由于活性成分剂量较低,作者认为Ovoresta M是现有口服避孕药的一个受欢迎的补充药物。

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