Allergic contact dermatitis from a novel diamino intermediate, 5-[(2-aminoethyl)thiomethyl]-N, N-dimethyl-2-furanmethanamine, in laboratory synthesis.

Allergic contact sensitivity to 5-[(2-aminoethyl)thiomethyl]-N, N-dimethyl-2-furanmethanamine, a diamino intermediate in the synthesis of a novel H2 antagonist, Ranitidine is reported in an industrial chemist with hand dermatitis, who had been working for a prolonged period on the conversion of this intermediate to its fumarate salt.