[酮洛芬对大鼠肝脏溶酶体的作用]
[Action of ketoprofen on hepatic lysosomes in the rat].
作者信息
Migne J, Vedrine Y, Bourat G, Fournel J, Heusse D
出版信息
Sem Hop. 1983 Dec 12;59(46):3204-7.
PMID:6318341
Abstract
Evidence for the stabilizing effect of ketoprofen on the lysosomal membrane is presented. Ketoprofen was as potent as indomethacin in stabilizing lysosomes subjected to changes in osmotic pressure. This effect was more marked in rats with adjuvant arthritis than in normal animals.
摘要
有证据表明酮洛芬对溶酶体膜具有稳定作用。在使溶酶体承受渗透压变化时，酮洛芬稳定溶酶体的效力与吲哚美辛相当。这种作用在佐剂性关节炎大鼠中比在正常动物中更为显著。
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