酮洛芬对大鼠肝脏溶酶体的作用。
Action of ketoprofen on hepatic lysosome in the rat.
作者信息
Migne J, Vedrine Y, Bourat G, Fournel J, Heusse D
出版信息
Rheumatol Rehabil. 1976;Suppl:15-9. doi: 10.1093/rheumatology/15.5.15.
PMID:1013580
Abstract
Evidence for the stabilizing effect of ketoprofen on the lysosomal membrane is presented. Ketoprofen was as potent as indomethacin in stabilizing lysosomes subjected to changes in osmotic pressure. This effect was more marked in rats with adjuvant arthritis than in normal animals.
摘要
本文提供了酮洛芬对溶酶体膜稳定作用的证据。在稳定遭受渗透压变化的溶酶体方面，酮洛芬与吲哚美辛的效力相当。这种作用在佐剂性关节炎大鼠中比在正常动物中更为明显。
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