Zubenko G S, Nixon R A
Am J Psychiatry. 1984 Jan;141(1):110-1. doi: 10.1176/ajp.141.1.110.
The use of captopril, an inhibitor of angiotensin-converting enzyme and enkephalinase, was associated with substantial mood elevation in three depressed patients. Substances that may alter neuropeptide synthesis or degradation warrant further investigation as therapeutic agents in certain neuropsychiatric disorders.
血管紧张素转换酶和脑啡肽酶抑制剂卡托普利的使用,在三名抑郁症患者中与情绪显著改善有关。可能改变神经肽合成或降解的物质,作为某些神经精神疾病的治疗药物值得进一步研究。