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大肠杆菌中焦磷酸的积累。与生长和核苷酸合成的关系。

Accumulation of pyrophosphate in Escherichia coli. Relationship to growth and nucleotide synthesis.

作者信息

Kukko E, Saarento H

出版信息

Arch Microbiol. 1983 Nov;136(3):209-11. doi: 10.1007/BF00409846.

DOI:10.1007/BF00409846
PMID:6318680
Abstract

Pyrophosphate (PPi) content of Escherichia coli is increased manyfold when the growth of the cells is limited by inhibition of the synthesis of nucleotides. The accumulated PPi is immediately degraded when inhibition is released and growth allowed to resume. Other tested nutritional deficiencies (starvation of carbon source, sulfate or an amino acid) fail to induce PPi accumulation.

摘要

当大肠杆菌细胞的生长因核苷酸合成受到抑制而受到限制时，其焦磷酸（PPi）含量会增加许多倍。当抑制解除并恢复生长时，积累的PPi会立即降解。其他经测试的营养缺陷（碳源、硫酸盐或氨基酸饥饿）均未能诱导PPi积累。

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本文引用的文献

1
Orotidylic acid decarboxylase: inhibition studies with azauridine 5'-phosphate.乳清苷酸脱羧酶：用5'-磷酸氮杂尿苷进行的抑制研究。
J Biol Chem. 1960 Oct;235:2917-9.
2
The intracellular concentration of pyrophosphate in the batch culture of Escherichia coli.大肠杆菌分批培养中焦磷酸的细胞内浓度。
Eur J Biochem. 1982 Oct;127(2):347-9. doi: 10.1111/j.1432-1033.1982.tb06878.x.
3
Changes in pools of acid-soluble phosphorus compounds induced by phosphorus starvation in Neurospora.粗糙脉孢菌中磷饥饿诱导的酸溶性磷化合物库的变化。
无乳链球菌中一种真核型激酶对嘌呤生物合成的调控
Mol Microbiol. 2005 Jun;56(5):1329-46. doi: 10.1111/j.1365-2958.2005.04620.x.
Mol Gen Genet. 1982;186(3):355-63. doi: 10.1007/BF00729454.
4
A method for the concentration and for the colorimetric determination of nanomoles of inorganic pyrophosphate.一种用于浓缩和比色测定无机焦磷酸纳摩尔数的方法。
Anal Biochem. 1981 Nov 1;117(2):293-300. doi: 10.1016/0003-2697(81)90725-9.
5
Accumulation of pyrophosphate and other energy-rich phosphorous compounds under various conditions of yeast growth.在酵母生长的各种条件下，焦磷酸和其他富含能量的磷化合物的积累。
Arch Microbiol. 1981 Feb;128(4):394-7. doi: 10.1007/BF00405919.
6
Effects of pyrophosphate, triphosphate, and potassium chloride on adenylate deaminase from rat muscle.焦磷酸盐、三磷酸盐和氯化钾对大鼠肌肉腺苷酸脱氨酶的影响。
Biochemistry. 1980 Sep 30;19(20):4564-7. doi: 10.1021/bi00561a004.
7
Relationship of free cytoplasmic pyrophosphate to liver glucose content and total pyrophosphate to cytoplasmic phosphorylation potential.游离细胞质焦磷酸与肝脏葡萄糖含量的关系以及总焦磷酸与细胞质磷酸化电位的关系。
FEBS Lett. 1980 Aug 25;117 Suppl:K65-72. doi: 10.1016/0014-5793(80)80571-0.
8
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Arch Biochem Biophys. 1980 Apr 15;201(1):256-8. doi: 10.1016/0003-9861(80)90521-4.
9
Culture medium for enterobacteria.用于肠道细菌的培养基。
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