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五种硅酸钙的体外巨噬细胞细胞毒性

In vitro macrophage cytotoxicity of five calcium silicates.

作者信息

Skaug V, Davies R, Gylseth B

出版信息

Br J Ind Med. 1984 Feb;41(1):116-21. doi: 10.1136/oem.41.1.116.

DOI:10.1136/oem.41.1.116
PMID:6318798
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1009245/
Abstract

Five calcium silicate minerals (two naturally occurring and three synthetic compounds) with defined morphology and chemical composition were compared for their cytotoxic and lysosomal enzyme releasing effects on unstimulated mouse peritoneal macrophages in vitro. One synthetic material, a fibrous tobermorite, was cytotoxic towards the cells, and two naturally occurring wollastonites induced selective release of beta-glucuronidase from the cells.

摘要

比较了五种具有特定形态和化学成分的硅酸钙矿物(两种天然矿物和三种合成化合物)对体外未刺激的小鼠腹腔巨噬细胞的细胞毒性和溶酶体酶释放作用。一种合成材料,纤维状雪硅钙石,对细胞具有细胞毒性,两种天然硅灰石诱导细胞选择性释放β-葡萄糖醛酸酶。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4554/1009245/b6a2adc440d5/brjindmed00049-0123-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4554/1009245/bde80408ffa0/brjindmed00049-0123-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4554/1009245/b6a2adc440d5/brjindmed00049-0123-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4554/1009245/bde80408ffa0/brjindmed00049-0123-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4554/1009245/b6a2adc440d5/brjindmed00049-0123-b.jpg

相似文献

1
In vitro macrophage cytotoxicity of five calcium silicates.五种硅酸钙的体外巨噬细胞细胞毒性
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Absence of genotoxic effects of nonasbestos mineral fibers.非石棉矿物纤维无遗传毒性作用。
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2
Gas supersaturation tolerances in amoeboid cells before and after ingestion of bubble-promoting particles.摄入促进气泡形成颗粒前后变形虫状细胞的气体过饱和度耐受性。
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本文引用的文献

1
Study of the toxicity of dust with use of the in vitro dehydrogenase technique.利用体外脱氢酶技术对粉尘毒性的研究。
AMA Arch Ind Health. 1959 Nov;20:383-9.
2
Uptake and digestion of horseradish peroxidase in rabbit alveolar macrophages. Formation of a pathway connecting lysosomes to the cell surface.辣根过氧化物酶在兔肺泡巨噬细胞中的摄取与消化。形成一条连接溶酶体与细胞表面的途径。
Lab Invest. 1982 Sep;47(3):235-46.
3
Relation of particle dimension to carcinogenicity in amphibole asbestoses and other fibrous minerals.闪石石棉及其他纤维状矿物质中颗粒尺寸与致癌性的关系。
J Natl Cancer Inst. 1981 Nov;67(5):965-75.
4
Hemolytic activity of five different calcium silicates.五种不同硅酸钙的溶血活性。
Environ Health Perspect. 1983 Sep;51:195-203. doi: 10.1289/ehp.8351195.
5
Wollastonite exposure and lung fibrosis.硅灰石暴露与肺纤维化。
Environ Res. 1983 Apr;30(2):291-304. doi: 10.1016/0013-9351(83)90215-3.
6
Biological reactivity of calcium silicate composites--in vitro studies.硅酸钙复合材料的生物反应性——体外研究
Environ Res. 1981 Oct;26(1):51-68. doi: 10.1016/0013-9351(81)90183-3.
7
On the determination of crystalline silica in the presence of amorphous silica.在无定形二氧化硅存在下对结晶二氧化硅的测定
Ann Occup Hyg. 1980;23(4):329-34. doi: 10.1093/annhyg/23.4.329.
8
The biological reactivity of calcium silicate composites: in vivo studies.
Environ Res. 1981 Dec;26(2):243-57. doi: 10.1016/0013-9351(81)90202-4.
9
A simple dispenser for generating dust clouds from standard reference samples of asbestos.一种用于从石棉标准参考样品中产生尘云的简易撒布器。
Ann Occup Hyg. 1968 Oct;11(4):273-81. doi: 10.1093/annhyg/11.4.273.
10
Release of lysosomal enzymes by alveolar mononuclear cells.肺泡单核细胞释放溶酶体酶。
Nature. 1974 Feb 15;247(5441):475-7. doi: 10.1038/247475a0.