五种硅酸钙的体外巨噬细胞细胞毒性

Skaug V, Davies R, Gylseth B

Br J Ind Med. 1984 Feb;41(1):116-21. doi: 10.1136/oem.41.1.116.

Five calcium silicate minerals (two naturally occurring and three synthetic compounds) with defined morphology and chemical composition were compared for their cytotoxic and lysosomal enzyme releasing effects on unstimulated mouse peritoneal macrophages in vitro. One synthetic material, a fibrous tobermorite, was cytotoxic towards the cells, and two naturally occurring wollastonites induced selective release of beta-glucuronidase from the cells.

比较了五种具有特定形态和化学成分的硅酸钙矿物（两种天然矿物和三种合成化合物）对体外未刺激的小鼠腹腔巨噬细胞的细胞毒性和溶酶体酶释放作用。一种合成材料，纤维状雪硅钙石，对细胞具有细胞毒性，两种天然硅灰石诱导细胞选择性释放β-葡萄糖醛酸酶。