Larsen M, Evans W K, Shepherd F A, Phillips M J, Bailey D, Messner H
Cancer. 1984 Feb 1;53(3):441-4. doi: 10.1002/1097-0142(19840201)53:3<441::aid-cncr2820530312>3.0.co;2-s.
The case of acute lymphoblastic leukemia developing shortly after the diagnosis and treatment of a mediastinal germ cell tumor, is reported. The close temporal relationship of these two rare diseases and the presence of a population of mononuclear cells with features of lymphoblasts in the resected germ cell tumor, suggest that the leukemic process originated from the mediastinal tumor.