转铁蛋白受体在小鼠造血祖细胞上的表达。
Expression of transferrin receptor on murine hematopoietic progenitors.
作者信息
Lesley J, Hyman R, Schulte R, Trotter J
出版信息
Cell Immunol. 1984 Jan;83(1):14-25. doi: 10.1016/0008-8749(84)90220-x.
We have used a monoclonal antibody against the murine transferrin receptor to study the expression of the transferrin receptor on the hematopoietic progenitor cells (BFU-E, CFU-E, and CFU-C) present in mouse bone marrow. Elutriation and cell-sorting data are consistent with the hypothesis that most CFU-E are transferrin receptor positive while most BFU-E express much less transferrin receptor. CFU-C comprise both transferrin-receptor-positive and -negative cells.
我们使用了一种针对小鼠转铁蛋白受体的单克隆抗体，来研究转铁蛋白受体在小鼠骨髓中存在的造血祖细胞（爆式红系集落形成单位、红系集落形成单位和粒系集落形成单位）上的表达情况。淘洗和细胞分选数据与以下假设一致：大多数红系集落形成单位是转铁蛋白受体阳性，而大多数爆式红系集落形成单位表达的转铁蛋白受体要少得多。粒系集落形成单位包括转铁蛋白受体阳性和阴性细胞。
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