Janský L
J Physiol (Paris). 1982;78(9):872-4.
It is concluded that besides NA, some other hormones (adrenaline, glucagon, growth hormone, ACTH, insulin and adrenal steroids) are also thermogenic. While brown adipose tissue is the most important site of heat during NA thermogenesis, some other organs, namely muscles, also contribute to thermogenesis due to various hormones. Hormones seem to potentiate heat production due to their action in target organs. Humoral thermogenesis not only can compensate the heat loss from the body of cold exposed individuals, but it can also prevent obesity under conditions of an high caloric intake. Some substance, on the other hand, induce a hypometabolic effect (rT3, hibernation trigger, antabolone, bombesin). Additionally, absence of gonadal steroids induce hibernation. Thus, humoral substances contribute both to the control of hyper- and hypometabolic states.
得出的结论是，除了去甲肾上腺素（NA）外，其他一些激素（肾上腺素、胰高血糖素、生长激素、促肾上腺皮质激素、胰岛素和肾上腺类固醇）也具有产热作用。虽然褐色脂肪组织是NA产热过程中最重要的产热部位，但其他一些器官，即肌肉，由于各种激素的作用也有助于产热。激素似乎因其在靶器官中的作用而增强产热。体液产热不仅可以补偿寒冷暴露个体身体的热量损失，而且在高热量摄入的情况下还可以预防肥胖。另一方面，某些物质会诱导低代谢效应（反式三碘甲状腺原氨酸、冬眠触发因子、抗代谢物、蛙皮素）。此外，性腺类固醇的缺乏会诱导冬眠。因此，体液物质对高代谢和低代谢状态的控制都有作用。
