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新纹状体的两个功能异质性水平。

Two levels of functional heterogeneity of the neostriatum.

作者信息

Divac I

出版信息

Neuroscience. 1983 Dec;10(4):1151-5. doi: 10.1016/0306-4522(83)90105-7.

DOI:10.1016/0306-4522(83)90105-7
PMID:6320045
Abstract

Autoradiography following administration of 2-deoxy-[14C]glucose has shown that penicillin-induced epileptic foci in the cerebral cortex selectively coactivate associated neostriatal regions. The present material demonstrates that this coactivation may appear in patches in the rat neostriatum. Activity from a cortical area seems to spread first to islands of the associated neostriatal region and may either spread gradually to the surrounding 'matrix' or not involve the 'matrix' for tenths of minutes. The regionally restricted functional patchiness lends additional support to the notion that the neostriatum, like the neocortex, can be divided into regions which consist of modules.

摘要

给予2-脱氧-[14C]葡萄糖后的放射自显影显示,青霉素诱导的大脑皮质癫痫病灶选择性地共同激活相关的新纹状体区域。目前的材料表明,这种共同激活可能以斑块形式出现在大鼠新纹状体中。来自皮质区域的活动似乎首先扩散到相关新纹状体区域的岛状结构,并且可能逐渐扩散到周围的“基质”,或者在十分之几分钟内不涉及“基质”。区域受限的功能性斑块为新纹状体与新皮质一样可分为由模块组成的区域这一观点提供了额外支持。

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