Klimenkov A A, Komov D V, Roshchin E M
Vopr Onkol. 1984;30(1):59-65.
The paper is concerned with the analysis of the results of surgical and drug therapy of 225 cases of primary hepatic tumor treated at the Center clinic within 1957-1981. 86 patients were operated on: radical surgery was performed in 20 cases. Postoperative lethality rate in radical surgery group was 10%, mean survival time-26.7 months. Systemic chemotherapy was given to 111, and regional one-to 12 patients. New schemes of drug treatment (carminomycin + bleomycin; preparations of platinum + other cytostatic drugs) were used in 30 cases. This was followed by a higher effectiveness of treatment and a longer survival, the latter being 9.0 +/- 1.3 months, as compared with 4.0 +/- 0.5 months in controls.
本文涉及对1957年至1981年期间在中心诊所接受治疗的225例原发性肝肿瘤患者的手术和药物治疗结果进行分析。86例患者接受了手术:其中20例进行了根治性手术。根治性手术组的术后死亡率为10%,平均生存时间为26.7个月。111例患者接受了全身化疗,12例接受了局部化疗。30例患者使用了新的药物治疗方案(卡米诺霉素+博来霉素;铂制剂+其他细胞毒性药物)。结果显示治疗效果更好,生存期更长,后者为9.0±1.3个月,而对照组为4.0±0.5个月。