细胞色素c介导的泛醇-细胞色素c还原酶与细胞色素c氧化酶之间的电子传递。细胞色素c可移动池的动力学证据。
Cytochrome c-mediated electron transfer between ubiquinol-cytochrome c reductase and cytochrome c oxidase. Kinetic evidence for a mobile cytochrome c pool.
作者信息
Froud R J, Ragan C I
出版信息
Biochem J. 1984 Jan 15;217(2):551-60. doi: 10.1042/bj2170551.
Abstract
Ubiquinol oxidase has been reconstituted from ubiquinol-cytochrome c reductase (Complex III), cytochrome c and cytochrome c oxidase (Complex IV). The steady-state level of reduction of cytochrome c by ubiquinol-2 varies with the molar ratios of the complexes and with the presence of antimycin in a way that can be quantitatively accounted for by a model in which cytochrome c acts as a freely diffusible pool on the membrane. This model was based on that of Kröger & Klingenberg [(1973) Eur. J. Biochem. 34, 358-368] for ubiquinone-pool behaviour. Further confirmation of the pool model was provided by analysis of ubiquinol oxidase activity as a function of the molar ratio of the complexes and prediction of the degree of inhibition by antimycin.
摘要
泛醇氧化酶已由泛醇 - 细胞色素c还原酶（复合体III）、细胞色素c和细胞色素c氧化酶（复合体IV）重构而成。泛醇 - 2对细胞色素c的稳态还原水平随复合体的摩尔比以及抗霉素的存在而变化，这种变化方式可以通过一个模型进行定量解释，在该模型中细胞色素c作为膜上自由扩散的库起作用。这个模型是基于Kröger和Klingenberg [（1973年）《欧洲生物化学杂志》34卷，358 - 368页]关于泛醌库行为的模型。通过分析泛醇氧化酶活性作为复合体摩尔比的函数以及预测抗霉素的抑制程度，进一步证实了库模型。
相似文献
1
Cytochrome c-mediated electron transfer between ubiquinol-cytochrome c reductase and cytochrome c oxidase. Kinetic evidence for a mobile cytochrome c pool.细胞色素c介导的泛醇-细胞色素c还原酶与细胞色素c氧化酶之间的电子传递。细胞色素c可移动池的动力学证据。
Biochem J. 1984 Jan 15;217(2):551-60. doi: 10.1042/bj2170551.
2
Properties of ubiquinol oxidase reconstituted from ubiquinol-cytochrome c reductase, cytochrome c and cytochrome c oxidase.由泛醇 - 细胞色素c还原酶、细胞色素c和细胞色素c氧化酶重构的泛醇氧化酶的性质。
Biochem J. 1982 Feb 15;202(2):527-34. doi: 10.1042/bj2020527.
3
The interaction between mitochondrial NADH-ubiquinone oxidoreductase and ubiquinol-cytochrome c oxidoreductase. Restoration of ubiquinone-pool behaviour.线粒体NADH-泛醌氧化还原酶与泛醇-细胞色素c氧化还原酶之间的相互作用。泛醌池行为的恢复。
Biochem J. 1978 Sep 15;174(3):791-800. doi: 10.1042/bj1740791.
4
Cytochrome c mediates electron transfer between ubiquinol-cytochrome c reductase and cytochrome c oxidase by free diffusion along the surface of the membrane.细胞色素c通过沿膜表面的自由扩散介导泛醌-细胞色素c还原酶和细胞色素c氧化酶之间的电子传递。
Biochem J. 1984 Jan 15;217(2):561-71. doi: 10.1042/bj2170561.
5
Structural and functional features of the interaction of cytochrome c with complex III and cytochrome c oxidase.细胞色素c与复合体III及细胞色素c氧化酶相互作用的结构和功能特征。
FEBS Lett. 1982 Feb 8;138(1):1-7. doi: 10.1016/0014-5793(82)80382-7.
6
The interaction between mitochondrial NADH-ubiquinone oxidoreductase and ubiquinol-cytochrome c oxidoreductase. Evidence for stoicheiometric association.线粒体NADH-泛醌氧化还原酶与泛醇-细胞色素c氧化还原酶之间的相互作用。化学计量关联的证据。
Biochem J. 1978 Sep 15;174(3):783-90. doi: 10.1042/bj1740783.
7
The reconstitution of L-3-glycerophosphate-cytochrome c oxidoreductase from L-3-glycerophosphate dehydrogenase, ubiquinone-10 and ubiquinol-cytochrome c oxidoreductase.由L-3-磷酸甘油脱氢酶、泛醌-10和泛醇-细胞色素c氧化还原酶重构L-3-磷酸甘油-细胞色素c氧化还原酶。
Biochem J. 1980 Oct 15;192(1):19-31. doi: 10.1042/bj1920019.
8
Redox Bohr-effects in isolated cytochrome bc1 complex and cytochrome c oxidase from beef-heart mitochondria.来自牛心线粒体的分离细胞色素bc1复合物和细胞色素c氧化酶中的氧化还原玻尔效应
FEBS Lett. 1981 Mar 23;125(2):261-5. doi: 10.1016/0014-5793(81)80734-x.
9
Kinetics and sidedness of ubiquinol-cytochrome c reductase in beef-heart mitochondria.牛心线粒体中泛醇 - 细胞色素c还原酶的动力学及方向性
FEBS Lett. 1982 Sep 6;146(1):101-5. doi: 10.1016/0014-5793(82)80713-8.
10
Evidence of ubisemiquinone radicals in electron transfer at the cytochromes b and c1 region of the cardiac respiratory chain.心脏呼吸链细胞色素b和c1区域电子传递过程中半醌自由基的证据。
Arch Biochem Biophys. 1980 Oct 1;204(1):59-70. doi: 10.1016/0003-9861(80)90007-7.
引用本文的文献
1
Mitochondria and Viral Infection: Advances and Emerging Battlefronts.线粒体与病毒感染：研究进展与新兴前沿领域。
mBio. 2022 Feb 22;13(1):e0209621. doi: 10.1128/mbio.02096-21. Epub 2022 Jan 25.
2
Cytochrome c mediates electron transfer between ubiquinol-cytochrome c reductase and cytochrome c oxidase by free diffusion along the surface of the membrane.细胞色素c通过沿膜表面的自由扩散介导泛醌-细胞色素c还原酶和细胞色素c氧化酶之间的电子传递。
Biochem J. 1984 Jan 15;217(2):561-71. doi: 10.1042/bj2170561.
3
Role of mobility of redox components in the inner mitochondrial membrane.氧化还原成分在线粒体内膜中的流动性作用。
J Membr Biol. 1988 Sep;104(3):193-209. doi: 10.1007/BF01872322.
本文引用的文献
1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
A generalised model for the equilibration of quinone pools with their biological donors and acceptors in membrane-bound electron transfer chains.膜结合电子传递链中醌池与其生物供体和受体平衡的通用模型。
FEBS Lett. 1981 Aug 3;130(2):173-8. doi: 10.1016/0014-5793(81)81113-1.
3
On the role of ubiquinone in the respiratory chain.论泛醌在呼吸链中的作用。
Biochim Biophys Acta. 1982 Apr 19;680(1):69-79. doi: 10.1016/0005-2728(82)90317-6.
4
Cytochrome c mediates electron transfer between ubiquinol-cytochrome c reductase and cytochrome c oxidase by free diffusion along the surface of the membrane.细胞色素c通过沿膜表面的自由扩散介导泛醌-细胞色素c还原酶和细胞色素c氧化酶之间的电子传递。
Biochem J. 1984 Jan 15;217(2):561-71. doi: 10.1042/bj2170561.
5
The effects of lipid fluidity on the rotational diffusion of complex I and complex III in reconstituted NADH-cytochrome c oxidoreductase.脂质流动性对重组NADH-细胞色素c氧化还原酶中复合物I和复合物III旋转扩散的影响。
Biochim Biophys Acta. 1982 Dec 8;693(1):113-24. doi: 10.1016/0005-2736(82)90477-1.
6
Rotational motion of cytochrome c derivatives bound to membranes measured by fluorescence and phosphorescence anisotropy.通过荧光和磷光各向异性测量与膜结合的细胞色素c衍生物的旋转运动。
Eur J Biochem. 1982 Aug;126(1):1-9. doi: 10.1111/j.1432-1033.1982.tb06737.x.
7
Properties of ubiquinol oxidase reconstituted from ubiquinol-cytochrome c reductase, cytochrome c and cytochrome c oxidase.由泛醇 - 细胞色素c还原酶、细胞色素c和细胞色素c氧化酶重构的泛醇氧化酶的性质。
Biochem J. 1982 Feb 15;202(2):527-34. doi: 10.1042/bj2020527.
8
The asymmetric distribution of charges on the surface of horse cytochrome c. Functional implications.马细胞色素c表面电荷的不对称分布。功能意义。
J Biol Chem. 1982 Apr 25;257(8):4426-37.
9
Structural and functional features of the interaction of cytochrome c with complex III and cytochrome c oxidase.细胞色素c与复合体III及细胞色素c氧化酶相互作用的结构和功能特征。
FEBS Lett. 1982 Feb 8;138(1):1-7. doi: 10.1016/0014-5793(82)80382-7.
Zotero 插件