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C4光合作用的调控：催化磷酸化是ADP介导的丙酮酸磷酸双激酶失活的前提条件。

Regulation of C4 photosynthesis: catalytic phosphorylation as a prerequisite for ADP-mediated inactivation of pyruvate,Pi dikinase.

作者信息

Burnell J N, Hatch M D

出版信息

Biochem Biophys Res Commun. 1984 Jan 13;118(1):65-72. doi: 10.1016/0006-291x(84)91068-4.

DOI:10.1016/0006-291x(84)91068-4
PMID:6320833
Abstract

Evidence is provided that the role of ATP in the ADP plus ATP-dependent inactivation of pyruvate,Pi dikinase is to catalytically phosphorylate the enzyme. Only this phosphorylated form of the enzyme is susceptible to inactivation by reacting with ADP. Phosphoenolpyruvate, which also phosphorylates pyruvate,Pi dikinase during catalysis, can replace the ATP-requirement for inactivation.

摘要

有证据表明，ATP在ADP加ATP依赖的丙酮酸、磷酸二激酶失活过程中的作用是催化该酶磷酸化。只有这种磷酸化形式的酶才易通过与ADP反应而失活。在催化过程中也能使丙酮酸、磷酸二激酶磷酸化的磷酸烯醇丙酮酸，可以替代失活所需的ATP。

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