Wordsworth B P, Pearcy M J, Mowat A G
Br J Rheumatol. 1984 Feb;23(1):39-43. doi: 10.1093/rheumatology/23.1.39.
Twenty-one patients with ankylosing spondylitis were admitted for two weeks bedrest, postural and mobilizing exercises. Eleven received low-dose corticotrophin and 10 received placebo injections during their admission and all were reviewed after two months. In-patient therapy resulted in significant improvements in function, early morning stiffness, spinal pain, lumbar extension and lateral flexion, finger-floor distance and wall-tragus distance. These improvements were maintained at two months. Biplanar radiography confirmed significant improvements of lumbar spine mobility in 14 male subjects studied. Less improvement occurred in neck movements and these were not maintained. There were no differences between the two treatment groups.
21例强直性脊柱炎患者入院接受为期两周的卧床休息、姿势矫正和活动锻炼。11例患者在住院期间接受小剂量促肾上腺皮质激素治疗，10例接受安慰剂注射，所有患者在两个月后接受复查。住院治疗使功能、晨僵、脊柱疼痛、腰椎前伸和侧屈、手指-地面距离和耳屏-墙壁距离有显著改善。这些改善在两个月时得以维持。双平面X线摄影证实，在研究的14名男性受试者中，腰椎活动度有显著改善。颈部活动改善较少且未得到维持。两个治疗组之间没有差异。
