Dagfinrud H, Kvien T K, Hagen K B
University of Oslo, Section for Health Science, P.O.box 1153, Blindern, Gydas vei 8, Oslo, Norway, 0316.
Cochrane Database Syst Rev. 2008 Jan 23;2008(1):CD002822. doi: 10.1002/14651858.CD002822.pub3.
Ankylosing spondylitis (AS) is a chronic, inflammatory rheumatic disease. Physiotherapy is considered an important part of the overall management of AS.
To summarise the available scientific evidence on the effectiveness of physiotherapy interventions in the management of AS.
We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, AMED, CINAHL and PEDro up to January 2007 for all relevant publications, without any language restrictions. We checked the reference lists of relevant articles and contacted the authors of included articles.
We included randomised and quasi-randomised studies with AS patients and where at least one of the comparison groups received physiotherapy. The main outcomes of interest were pain, stiffness, spinal mobility, physical function and patient global assessment.
Two reviewers independently selected trials for inclusion, extracted data and assessed trial quality. Investigators were contacted to obtain missing information.
Eleven trials with a total of 763 participants were included in this updated review. Four trials compared individualised home exercise programs or a supervised exercise program with no intervention and reported low quality evidence for effects in spinal mobility (Relative percentage differences (RPDs) from 5-50%) and physical function (four points on a 33-point scale). Three trials compared supervised group physiotherapy with an individualised home-exercise program and reported moderate quality evidence for small differences in spinal mobility (RPDs 7.5-18%) and patient global assessment (1.46 cm) in favour of supervised group exercises. In one study, a three-week inpatient spa-exercise therapy followed by 37 weeks of weekly outpatient group physiotherapy (without spa) was compared with weekly outpatient group physiotherapy alone; there was moderate quality evidence for effects in pain (18%), physical function (24%) and patient global assessment (27%) in favour of the combined spa-exercise therapy. One study compared daily outpatient balneotherapy and an exercise program with only exercise program, and another study compared balneotherapy with fresh water therapy. None of these studies showed significant between-group differences. One study compared an experimental exercise program with a conventional program; statistically significant change scores were reported on nearly all spinal mobility measures and physical function in favour of the experimental program.
AUTHORS' CONCLUSIONS: The results of this review suggest that an individual home-based or supervised exercise program is better than no intervention; that supervised group physiotherapy is better than home exercises; and that combined inpatient spa-exercise therapy followed by group physiotherapy is better than group physiotherapy alone.
强直性脊柱炎(AS)是一种慢性炎症性风湿性疾病。物理治疗被认为是AS综合管理的重要组成部分。
总结物理治疗干预措施在AS管理中有效性的现有科学证据。
我们检索了截至2007年1月的Cochrane对照试验中心注册库(CENTRAL)、MEDLINE、EMBASE、AMED、CINAHL和PEDro,以获取所有相关出版物,无任何语言限制。我们检查了相关文章的参考文献列表,并联系了纳入文章的作者。
我们纳入了针对AS患者的随机和半随机研究,且至少有一个比较组接受了物理治疗。主要关注的结局包括疼痛、僵硬、脊柱活动度、身体功能和患者整体评估。
两名综述作者独立选择纳入试验、提取数据并评估试验质量。联系研究者以获取缺失信息。
本次更新综述纳入了11项试验,共763名参与者。4项试验将个体化家庭锻炼计划或监督锻炼计划与无干预进行比较,报告了关于脊柱活动度(相对百分比差异(RPDs)为5 - 50%)和身体功能(33分制量表上4分)影响的低质量证据。3项试验将监督性团体物理治疗与个体化家庭锻炼计划进行比较,报告了中等质量证据,表明在脊柱活动度(RPDs为7.5 - 18%)和患者整体评估(1.46 cm)方面存在小的差异,支持监督性团体锻炼。在一项研究中,将为期三周的住院温泉 - 锻炼疗法,随后37周的每周门诊团体物理治疗(无温泉)与单独的每周门诊团体物理治疗进行比较;有中等质量证据表明在疼痛(18%)、身体功能(24%)和患者整体评估(27%)方面有效果,支持联合温泉 - 锻炼疗法。一项研究比较了每日门诊水疗和锻炼计划与仅锻炼计划,另一项研究比较了水疗与淡水疗法。这些研究均未显示组间有显著差异。一项研究将实验性锻炼计划与传统计划进行比较;几乎所有脊柱活动度测量指标和身体功能方面均报告了具有统计学意义的变化分数,支持实验性计划。
本综述结果表明,个体化家庭或监督锻炼计划优于无干预;监督性团体物理治疗优于家庭锻炼;住院温泉 - 锻炼疗法联合团体物理治疗优于单独的团体物理治疗。