Martin-Dupont P, Imbert Y, Laurentjoye P, Dupuy-Braud E, Leng B
Sem Hop. 1984 Feb 16;60(8):534-7.
The authors report 2 cases of autoimmune hemolytic anemia (AHA) and Hodgkin disease. The Hodgkin disease often precedes AHA. Most patients are found to have extensive disease; histologic features are classified as being of high grades of malignancy (mixed cellularity and nodular sclerosis types). Anti I, Rh, IgG auto antibody is commonly observed at 37 degrees C. AHA and Hodgkin disease are equally improved by chemotherapy. The prognosis and significance of this pathological association are unclear.
作者报告了2例自身免疫性溶血性贫血(AHA)合并霍奇金病的病例。霍奇金病常先于AHA出现。多数患者被发现有广泛病变;组织学特征被归类为高恶性度(混合细胞型和结节硬化型)。在37℃时通常可观察到抗I、Rh、IgG自身抗体。化疗可使AHA和霍奇金病同样得到改善。这种病理关联的预后及意义尚不清楚。