Jooma R, Kendall B E, Hayward R D
Surg Neurol. 1984 Feb;21(2):165-70. doi: 10.1016/0090-3019(84)90336-7.
Seventeen patients with intracranial neoplasms that were symptomatic within the first 2 months of life were studied. Macrocrania was the commonest clinical feature, and radiologic studies including computed tomographic examination in five of the patients, showed that the tumors tended to be large, rapidly growing, and located along the neural axis. The outlook was poor, with a high operative and case mortality. The risks of irradiating young infants are discussed, and a conservative surgical approach with careful case selection is advocated.
对17例在出生后2个月内出现症状的颅内肿瘤患儿进行了研究。巨头畸形是最常见的临床特征，包括5例患儿的计算机断层扫描在内的放射学研究表明，肿瘤往往体积较大、生长迅速且沿神经轴分布。预后较差，手术死亡率和病例死亡率都很高。讨论了对幼儿进行放疗的风险，并提倡采用保守的手术方法并谨慎选择病例。
