牛髓鞘碱性蛋白N端部分在兔体内的致脑炎性活性。
Encephalitogenic activity of the N-terminal part of bovine myelin basic protein in rabbits.
作者信息
Bergstrand H
出版信息
Acta Pathol Microbiol Scand C. 1976 Dec;84C(6):442-6. doi: 10.1111/j.1699-0463.1976.tb00053.x.
Abstract
The disease-inducing activity of the N-terminal part (residues 1-42) of bovine myelin basic protein in rabbits is localized to two regions. One encephalitogenic determined probably incorporates at least one of the lysine residues (Nos. 4 and 11); the other is within residues 20-36. It is concluded that region 1-42 shows a comparably strong degree of encephalitogenicity for rabbits.
摘要
牛髓鞘碱性蛋白N端部分（第1 - 42位氨基酸残基）在兔体内的致疾病活性定位于两个区域。一个致脑炎性决定簇可能至少包含一个赖氨酸残基（第4和11位）；另一个在第20 - 36位氨基酸残基范围内。得出的结论是，1 - 42区域对兔显示出相当强的致脑炎性程度。
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