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[肾源性环磷酸腺苷测定的诊断价值及颈部超声检查在原发性甲状旁腺功能亢进症定位诊断中的价值。附13例报告]

[Diagnostic value of the determination of nephrogenic cyclic AMP, and the value of cervical echography for localization in primary hyperparathyroidism. 13 cases].

作者信息

Bentata-Pessayre M, Krivitzky A, Fond B, Gardin J P, Poncin J, Delzant G

出版信息

Ann Med Interne (Paris). 1984;135(1):7-11.

PMID:6322640
Abstract

The authors report the cases of 13 patients with parathyroid adenomas and hyperparathyroidism. They estimate that this disease may be observed in about 70/100,000 patients hospitalised in a non-specialised medical department. In four of these patients, the disease was asymptomatic while only four patients presented with symptomatic renal stones. In five patients, immuno reactive parathyroid hormone levels were within normal limits. In contrast, nephrogenic cyclic AMP, measured in 11 patients, was found to be increased in the totality of these patients and could not be decreased by the administration of calcium. An ultrasonographic examination of the neck, performed in 11 patients, showed the adenomas in 6 patients; in three other patients they were located in the neck but measured less than 1 cm in their greater diameter and in other two patients the adenomas were located in the thymus.

摘要

作者报告了13例甲状旁腺腺瘤和甲状旁腺功能亢进患者的病例。他们估计,在非专科医疗科室住院的患者中,每10万人中约有70人可能患有这种疾病。在这些患者中,有4例无症状,只有4例出现有症状的肾结石。5例患者的免疫反应性甲状旁腺激素水平在正常范围内。相比之下,在11例患者中检测的肾源性环磷酸腺苷在所有这些患者中均升高,且给予钙剂后不能降低。对11例患者进行的颈部超声检查显示,6例患者有腺瘤;另外3例位于颈部,但最大直径小于1厘米,还有2例腺瘤位于胸腺。

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