苯环利定及其类似物对突触体多巴胺摄取抑制作用中的结构-功能关系：与用[3H]苯环利定鉴定的结合位点的潜在相关性 - Suppr

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超能文献

Structure-function relationships in the inhibition of synaptosomal dopamine uptake by phencyclidine and analogues: potential correlation with binding site identified with [3H]phencyclidine.

作者信息

Vignon J, Lazdunski M

出版信息

Biochem Pharmacol. 1984 Feb 15;33(4):700-2. doi: 10.1016/0006-2952(84)90333-2.

DOI:10.1016/0006-2952(84)90333-2

PMID:6322809

Abstract

摘要

相似文献

Structure-function relationships in the inhibition of synaptosomal dopamine uptake by phencyclidine and analogues: potential correlation with binding site identified with [3H]phencyclidine.苯环利定及其类似物对突触体多巴胺摄取抑制作用中的结构-功能关系：与用[3H]苯环利定鉴定的结合位点的潜在相关性

Biochem Pharmacol. 1984 Feb 15;33(4):700-2. doi: 10.1016/0006-2952(84)90333-2.

Phencyclidine (PCP)-like inhibition of N-methyl-D-aspartate-evoked striatal acetylcholine release, H-TCP binding and synaptosomal dopamine uptake by metaphit, a proposed PCP receptor acylator.苯环利定（PCP）样抑制N-甲基-D-天冬氨酸诱发的纹状体乙酰胆碱释放、H-TCP结合以及被认为是PCP受体酰化剂的美沙吡啉对突触体多巴胺的摄取。

Life Sci. 1987 Dec 14;41(24):2645-54. doi: 10.1016/0024-3205(87)90279-7.

Role of the aromatic group in the inhibition of phencyclidine binding and dopamine uptake by PCP analogs.芳香基团在苯环己哌啶类似物抑制苯环己哌啶结合及多巴胺摄取中的作用。

Pharmacol Biochem Behav. 1989 Mar;32(3):699-705. doi: 10.1016/0091-3057(89)90020-8.

Effects of phencyclidine (PCP)-like drugs on turning behavior, 3H-dopamine uptake, and 3H-PCP binding.

Pharmacol Biochem Behav. 1985 May;22(5):731-5. doi: 10.1016/0091-3057(85)90521-0.

The psychotomimetic drug phencyclidine labels two high affinity binding sites in guinea pig brain: evidence for N-methyl-D-aspartate-coupled and dopamine reuptake carrier-associated phencyclidine binding sites.拟精神病药物苯环己哌啶在豚鼠脑中标记出两个高亲和力结合位点：N-甲基-D-天冬氨酸偶联的和多巴胺再摄取载体相关的苯环己哌啶结合位点的证据。

Mol Pharmacol. 1989 Dec;36(6):887-96.

Chronic phencyclidine treatment decreases phencyclidine and dopamine receptors in rat brain.长期给予苯环己哌啶会降低大鼠脑中的苯环己哌啶和多巴胺受体。

Pharmacol Biochem Behav. 1982 Oct;17(4):699-702. doi: 10.1016/0091-3057(82)90349-5.

Phencyclidine in nanomolar concentrations binds to synaptosomes and blocks certain potassium channels.纳摩尔浓度的苯环利定与突触体结合并阻断某些钾通道。

Proc Natl Acad Sci U S A. 1983 Jun;80(12):3855-9. doi: 10.1073/pnas.80.12.3855.

A specific acylating agent for the [3H]phencyclidine receptors in rat brain.一种针对大鼠脑内[3H]苯环利定受体的特异性酰化剂。

FEBS Lett. 1985 Feb 25;181(2):318-22. doi: 10.1016/0014-5793(85)80284-2.

Effects of the major metabolite of phencyclidine, the trans isomer of 4-phenyl-4-(1-piperidinyl)cyclohexanol, on [3H]N-(1-[2-thienyl] cyclohexyl)-3,4-piperidine ([3H]TCP) binding and [3H]dopamine uptake in the rat brain.

Neurosci Lett. 1994 Nov 21;182(1):119-21. doi: 10.1016/0304-3940(94)90221-6.

Metaphit inhibits dopamine transport and binding of [3H]methylphenidate, a proposed marker for the dopamine transport complex.灭草喹抑制多巴胺转运以及[3H]哌醋甲酯的结合，[3H]哌醋甲酯是一种多巴胺转运复合体的假定标志物。

Life Sci. 1989;45(18):1689-98. doi: 10.1016/0024-3205(89)90279-8.

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CNS Drug Rev. 2001 Summer;7(2):172-98. doi: 10.1111/j.1527-3458.2001.tb00194.x.

An electrophilic affinity ligand based on (+)-MK801 distinguishes PCP site 1 from PCP site 2.一种基于（+）-MK801的亲电亲和配体区分了PCP位点1和PCP位点2。

Neurochem Res. 1994 Apr;19(4):385-9. doi: 10.1007/BF00967314.

Phencyclidine. Physiological actions, interactions with excitatory amino acids and endogenous ligands.苯环利定。生理作用、与兴奋性氨基酸及内源性配体的相互作用。

Mol Neurobiol. 1987 Fall;1(3):191-211. doi: 10.1007/BF02936608.

Role of the sigma receptor in the inhibition of [3H]-noradrenaline uptake in brain synaptosomes and adrenal chromaffin cells.σ受体在抑制脑突触体和肾上腺嗜铬细胞中[³H]-去甲肾上腺素摄取中的作用。

Br J Pharmacol. 1991 Aug;103(4):1917-22. doi: 10.1111/j.1476-5381.1991.tb12352.x.

Central non-opioid physiological and pathophysiological effects of dynorphin A and related peptides.强啡肽A及相关肽的中枢非阿片类生理和病理生理作用。

J Psychiatry Neurosci. 1992 Sep;17(3):106-19.

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