Yanase S, Ito Y
Cancer Lett. 1984 Mar;22(2):183-6. doi: 10.1016/0304-3835(84)90116-2.
12-O-Tetradecanoyl-phorbol-13-acetate (TPA), 12-O-hexadecanoyl-16-hydrophorbol-13-acetate (HHPA), croton oil, tung oil and Croton megalocarpus ether extract, all of which are known to possess Epstein-Barr virus-activating potency, retained their capacity to induce Epstein-Barr virus early antigen complex in the viral genome-carrying human lymphoblastoid cells (Raji) even after heat treatment at 120 degrees C for 2 h or at 100 degrees C for 12 h. Such unusual heat resistance of the agents tested may contribute to the persistence and accumulation of the active principle(s) in soil under the plants which contain such substances, as we have previously reported.
12-氧-十四烷酰佛波醇-13-乙酸酯（TPA）、12-氧-十六烷酰-16-羟基佛波醇-13-乙酸酯（HHPA）、巴豆油、桐油和大果巴豆醚提取物，所有这些物质都已知具有激活爱泼斯坦-巴尔病毒的能力，即使在120℃热处理2小时或100℃热处理12小时后，它们仍能在携带病毒基因组的人淋巴母细胞（拉吉细胞）中诱导爱泼斯坦-巴尔病毒早期抗原复合物。如我们之前所报道的，所测试的这些物质这种不同寻常的耐热性可能有助于活性成分在含有此类物质的植物下的土壤中持续存在和积累。
