Machin G A, McCaughey W T
Histopathology. 1984 Jan;8(1):35-53. doi: 10.1111/j.1365-2559.1984.tb02320.x.
Almost half of the kidneys containing Wilms' tumours also contain persistent renal blastema in one or more of its forms. Persistent renal blastema is present in almost all cases of bilateral nephroblastoma. Multifocal superficial nephroblastemomatosis is the best known form of persistent renal blastema, and there is good evidence that it is a precursor of nephroblastoma. This paper reports four cases of a second, deep cortical type of nephroblastomatosis. This type of persistent renal blastema appears to be a precursor of a distinct histologic subtype of nephroblastoma, and differs from multifocal superficial nephroblastomatosis also in its teratological background.
几乎一半含有肾母细胞瘤的肾脏还含有一种或多种形式的持续性肾胚基。持续性肾胚基几乎存在于所有双侧肾母细胞瘤病例中。多灶性浅表性肾母细胞瘤病是持续性肾胚基最广为人知的形式，而且有充分证据表明它是肾母细胞瘤的前驱病变。本文报告了4例第二种类型的、深部皮质型肾母细胞瘤病。这种类型的持续性肾胚基似乎是肾母细胞瘤一种独特组织学亚型的前驱病变，并且在致畸学背景方面也与多灶性浅表性肾母细胞瘤病有所不同。
