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一例无已知危险因素患者的获得性免疫缺陷综合征：一项病理学研究

Acquired immunodeficiency syndrome in a patient with no known risk factors: a pathological study.

作者信息

Burt A D, Scott G, Shiach C R, Isles C G

出版信息

J Clin Pathol. 1984 Apr;37(4):471-4. doi: 10.1136/jcp.37.4.471.

DOI:10.1136/jcp.37.4.471
PMID:6323550
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC498755/
Abstract

We present the pathological findings in a case of acquired immunodeficiency syndrome (AIDS) in a patient with no known risk factor. Postmortem examination showed klebsiella lung abscess, generalised cytomegalovirus infection, cerebral toxoplasmosis, and a primary cerebral lymphoma. An additional feature was the presence of dilatation of the intrahepatic large bile ducts in association with an atypical distribution of cytomegalovirus. The relation between this case and previously reported cases of AIDS is discussed.

摘要

我们报告了一例无已知危险因素的获得性免疫缺陷综合征（AIDS）患者的病理检查结果。尸检显示有克雷伯菌肺脓肿、全身性巨细胞病毒感染、脑弓形虫病和原发性脑淋巴瘤。另一个特征是肝内大胆管扩张并伴有巨细胞病毒的非典型分布。本文讨论了该病例与先前报道的艾滋病病例之间的关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e547/498755/481570f48040/jclinpath00175-0117-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e547/498755/0223d5b01951/jclinpath00175-0116-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e547/498755/dbd0d02e060c/jclinpath00175-0116-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e547/498755/52aaa964dcfe/jclinpath00175-0116-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e547/498755/481570f48040/jclinpath00175-0117-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e547/498755/0223d5b01951/jclinpath00175-0116-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e547/498755/dbd0d02e060c/jclinpath00175-0116-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e547/498755/52aaa964dcfe/jclinpath00175-0116-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e547/498755/481570f48040/jclinpath00175-0117-a.jpg

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1
Acquired immunodeficiency syndrome in a patient with no known risk factors: a pathological study.一例无已知危险因素患者的获得性免疫缺陷综合征：一项病理学研究
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引用本文的文献

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2
Difficulties in the diagnosis of acquired immune deficiency syndrome.获得性免疫缺陷综合征的诊断难点。
J Clin Pathol. 1984 Nov;37(11):1316-7. doi: 10.1136/jcp.37.11.1316.
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[Deliberations and computer computations on the epidemiology of the acquired immunodeficiency syndrome in the Federal Republic of Germany].

本文引用的文献

1
An outbreak of community-acquired Pneumocystis carinii pneumonia: initial manifestation of cellular immune dysfunction.社区获得性卡氏肺孢子虫肺炎暴发：细胞免疫功能障碍的初始表现。
N Engl J Med. 1981 Dec 10;305(24):1431-8. doi: 10.1056/NEJM198112103052402.
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Primary lymphoma of the nervous system associated with acquired immune-deficiency syndrome.
N Engl J Med. 1983 Jan 6;308(1):45. doi: 10.1056/NEJM198301063080112.
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Acquired immune deficiency syndrome.获得性免疫缺陷综合征
Infection. 1986 Sep-Oct;14(5):217-22. doi: 10.1007/BF01644266.
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Cholangitis in the acquired immunodeficiency syndrome: report of two cases and review of the literature.获得性免疫缺陷综合征中的胆管炎：两例报告并文献复习。
Gut. 1987 Dec;28(12):1653-60. doi: 10.1136/gut.28.12.1653.
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Cytomegalovirus infection of the thyroid in immunocompromised adults.免疫功能低下成人甲状腺的巨细胞病毒感染
Yale J Biol Med. 1987 Jan-Feb;60(1):1-8.
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Sonographic diagnosis of cholangitis in AIDS patients.
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Acquired immunodeficiency syndrome with Pneumocystis carinii pneumonia and Mycobacterium avium-intracellulare infection in a previously healthy patient with classic hemophilia. Clinical, immunologic, and virologic findings.一名既往健康的典型血友病患者发生获得性免疫缺陷综合征，合并卡氏肺孢子虫肺炎和鸟分枝杆菌复合群感染。临床、免疫学及病毒学检查结果
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Cutaneous cytomegalovirus vasculitis: an unusual clinical presentation of a common opportunistic pathogen.
Hum Pathol. 1982 Dec;13(12):1138-41. doi: 10.1016/s0046-8177(82)80254-2.
6
Clinical spectrum of lymphoproliferative disorders in renal transplant recipients and evidence for the role of Epstein-Barr virus.肾移植受者淋巴增生性疾病的临床谱及爱泼斯坦-巴尔病毒作用的证据
Cancer Res. 1981 Nov;41(11 Pt 1):4253-61.
7
Acquired immune deficiency in Haitians: opportunistic infections in previously healthy Haitian immigrants.海地人的获得性免疫缺陷：既往健康的海地移民中的机会性感染。
N Engl J Med. 1983 Jan 20;308(3):125-9. doi: 10.1056/NEJM198301203080303.
8
Occult infections with M. intracellulare in bone-marrow biopsy specimens from patients with AIDS.
N Engl J Med. 1983 Jun 16;308(24):1475-6. doi: 10.1056/NEJM198306163082411.
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Outbreak of central-nervous-system toxoplasmosis in western Europe and North America.西欧和北美的中枢神经系统弓形虫病暴发。
Lancet. 1983 Apr 9;1(8328):781-4. doi: 10.1016/s0140-6736(83)91847-0.
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Acquired immunodeficiency syndrome in France.
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