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臭氧处理的犬甲状旁腺主细胞中出现马洛里小体样包涵体。

Occurrence of Mallory body-like inclusions in parathyroid chief cells of ozone-treated dogs.

作者信息

Atwal O S, Pemsingh R S

出版信息

J Pathol. 1984 Mar;142(3):169-74. doi: 10.1002/path.1711420304.

DOI:10.1002/path.1711420304
PMID:6323660
Abstract

Ultrastructural characteristics of chief cells of the parathyroid glands of ozone-treated dogs were examined 3 days, 10-13 days and 28 days after treatment. Dilated Golgi cisternae and vacuoles contained low electron dense fibrillar material. These changes in the Golgi were accompanied by massive accumulation of filaments in the perinuclear area where most of the cell organelles were disrupted to the peripheral zone of the filamentous inclusions. These inclusions were not enclosed by a membrane and corresponded with PAS-positive and diastase-resistant material in the chief cells at light microscopic level. Therefore these inclusions were arbitrarily designated as Mallory body-like inclusions.

摘要

在臭氧处理犬的甲状旁腺主细胞的超微结构特征在处理后3天、10 - 13天和28天进行了检查。扩张的高尔基池和液泡含有低电子密度的纤维状物质。高尔基器的这些变化伴随着核周区域细丝的大量积累,其中大多数细胞器被破坏到丝状内含物的外周区域。这些内含物没有被膜包裹,在光学显微镜水平上与主细胞中PAS阳性且抗淀粉酶的物质相对应。因此,这些内含物被随意指定为马洛里小体样内含物。

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