水疱性口炎病毒内部缺失突变体合成的异常糖蛋白信使核糖核酸的核苷酸序列。
Nucleotide sequence of an aberrant glycoprotein mRNA synthesized by the internal deletion mutant of vesicular stomatitis virus.
作者信息
Herman R C
出版信息
J Virol. 1984 May;50(2):524-8. doi: 10.1128/JVI.50.2.524-528.1984.
Abstract
The transcriptionally active internal deletion mutant (DI-LT) of vesicular stomatitis virus synthesizes an abnormal mRNA (G*) containing a transcript of the remnant polymerase gene covalently linked to the 3' end of the glycoprotein message (R.C. Herman and R.A. Lazzarini, J. Virol. 40:78-86, 1981). A complementary DNA copy of the 3' end of the G* transcript was molecularly cloned and then chemically sequenced. The results showed that the deletion removed the last 54 nucleotides of the normal glycoprotein gene, the intergenic dinucleotide, and all but the last 258 nucleotides of the polymerase gene. The sequence of DI-LT at the deletion site was compared to that of the transcriptionally inactive DI-LT2 particle.
摘要
水泡性口炎病毒的转录活性内部缺失突变体（DI-LT）合成一种异常mRNA（G*），其包含与糖蛋白信息3'端共价连接的残余聚合酶基因转录本（R.C.赫尔曼和R.A.拉扎里尼，《病毒学杂志》40:78 - 86，1981）。G*转录本3'端的互补DNA拷贝进行了分子克隆，然后进行化学测序。结果表明，该缺失去除了正常糖蛋白基因的最后54个核苷酸、基因间二核苷酸以及聚合酶基因除最后258个核苷酸之外的所有部分。将缺失位点处DI-LT的序列与转录无活性的DI-LT2颗粒的序列进行了比较。
相似文献
1
Nucleotide sequence of an aberrant glycoprotein mRNA synthesized by the internal deletion mutant of vesicular stomatitis virus.水疱性口炎病毒内部缺失突变体合成的异常糖蛋白信使核糖核酸的核苷酸序列。
J Virol. 1984 May;50(2):524-8. doi: 10.1128/JVI.50.2.524-528.1984.
2
Aberrant glycoprotein mRNA synthesized by the internal deletion mutant of vesicular stomatitis virus.由水疱性口炎病毒内部缺失突变体合成的异常糖蛋白信使核糖核酸。
J Virol. 1981 Oct;40(1):78-86. doi: 10.1128/JVI.40.1.78-86.1981.
3
Conditional synthesis of an aberrant glycoprotein mRNA by the internal deletion mutant of vesicular stomatitis virus.水泡性口炎病毒内部缺失突变体对异常糖蛋白mRNA的条件性合成。
J Virol. 1983 Jun;46(3):709-17. doi: 10.1128/JVI.46.3.709-717.1983.
4
Oligonucleotide sequence analyses indicate that vesicular stomatitis virus large defective interfering virus particle RNA is made by internal deletion: evidence for similar transcription polyadenylation signals for the synthesis of all vesicular stomatitis virus mRNA species.寡核苷酸序列分析表明，水泡性口炎病毒大型缺陷干扰病毒颗粒RNA是通过内部缺失产生的：合成所有水泡性口炎病毒mRNA种类的转录多聚腺苷酸化信号相似的证据。
J Virol. 1980 Feb;33(2):807-17. doi: 10.1128/JVI.33.2.807-817.1980.
5
Vesicular stomatitis virus defective interfering particle containing a muted internal leader RNA gene.含有沉默内部引导RNA基因的水疱性口炎病毒缺陷干扰颗粒。
Proc Natl Acad Sci U S A. 1981 Apr;78(4):2090-4. doi: 10.1073/pnas.78.4.2090.
6
Sequence signal involved in the generation of an internally deleted defective interfering RNA from vesicular stomatitis virus.参与从水疱性口炎病毒产生内部缺失的缺陷干扰RNA的序列信号。
Nucleic Acids Res. 1982 Nov 11;10(21):6919-30. doi: 10.1093/nar/10.21.6919.
7
Mutational analyses of the intergenic dinucleotide and the transcriptional start sequence of vesicular stomatitis virus (VSV) define sequences required for efficient termination and initiation of VSV transcripts.水泡性口炎病毒（VSV）基因间二核苷酸和转录起始序列的突变分析确定了VSV转录本有效终止和起始所需的序列。
J Virol. 1997 Mar;71(3):2127-37. doi: 10.1128/JVI.71.3.2127-2137.1997.
8
Sites of copy choice replication involved in generation of vesicular stomatitis virus defective-interfering particle RNAs.参与水疱性口炎病毒缺陷干扰颗粒RNA产生的复制选择位点。
J Virol. 1984 Aug;51(2):515-21. doi: 10.1128/JVI.51.2.515-521.1984.
9
RNA polymerase-associated interactions near template promoter sequences of defective interfering particles of vesicular stomatitis virus.水疱性口炎病毒缺陷干扰颗粒模板启动子序列附近的RNA聚合酶相关相互作用。
J Virol. 1982 Jul;43(1):241-9. doi: 10.1128/JVI.43.1.241-249.1982.
10
Identification of an upstream sequence element required for vesicular stomatitis virus mRNA transcription.鉴定水泡性口炎病毒mRNA转录所需的上游序列元件。
J Virol. 2002 Aug;76(15):7632-41. doi: 10.1128/jvi.76.15.7632-7641.2002.
引用本文的文献
1
Sites of copy choice replication involved in generation of vesicular stomatitis virus defective-interfering particle RNAs.参与水疱性口炎病毒缺陷干扰颗粒RNA产生的复制选择位点。
J Virol. 1984 Aug;51(2):515-21. doi: 10.1128/JVI.51.2.515-521.1984.
本文引用的文献
1
M13 bacteriophage and pUC plasmids containing DNA inserts but still capable of beta-galactosidase alpha-complementation.含有DNA插入片段但仍能进行β-半乳糖苷酶α-互补的M13噬菌体和pUC质粒。
Gene. 1983 Aug;23(2):131-6. doi: 10.1016/0378-1119(83)90044-6.
2
Analysis of the recombination event generating a vesicular stomatitis virus deletion defective interfering particle.产生水疱性口炎病毒缺失型缺陷干扰颗粒的重组事件分析。
J Virol. 1983 Feb;45(2):766-72. doi: 10.1128/JVI.45.2.766-772.1983.
3
The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers.pUC质粒，一种源自M13mp7的用于插入诱变和使用合成通用引物进行测序的系统。
Gene. 1982 Oct;19(3):259-68. doi: 10.1016/0378-1119(82)90015-4.
4
Sequence signal involved in the generation of an internally deleted defective interfering RNA from vesicular stomatitis virus.参与从水疱性口炎病毒产生内部缺失的缺陷干扰RNA的序列信号。
Nucleic Acids Res. 1982 Nov 11;10(21):6919-30. doi: 10.1093/nar/10.21.6919.
5
In vitro and in vivo inhibition of primary transcription of vesicular stomatitis virus by a defective interfering particle.一种缺陷干扰颗粒对水疱性口炎病毒初级转录的体外和体内抑制作用
J Virol. 1982 Jan;41(1):172-82. doi: 10.1128/JVI.41.1.172-182.1982.
6
pUR222, a vector for cloning and rapid chemical sequencing of DNA.pUR222，一种用于DNA克隆和快速化学测序的载体。
Nucleic Acids Res. 1981 Aug 25;9(16):4087-98. doi: 10.1093/nar/9.16.4087.
7
Aberrant glycoprotein mRNA synthesized by the internal deletion mutant of vesicular stomatitis virus.由水疱性口炎病毒内部缺失突变体合成的异常糖蛋白信使核糖核酸。
J Virol. 1981 Oct;40(1):78-86. doi: 10.1128/JVI.40.1.78-86.1981.
8
Nucleotide sequences of the mRNA's encoding the vesicular stomatitis virus G and M proteins determined from cDNA clones containing the complete coding regions.从包含完整编码区的cDNA克隆中确定的编码水疱性口炎病毒G蛋白和M蛋白的mRNA的核苷酸序列。
J Virol. 1981 Aug;39(2):519-28. doi: 10.1128/JVI.39.2.519-528.1981.
9
Vesicular stomatitis virus RNA polymerase can read through the boundary between the leader and N genes in vitro.水疱性口炎病毒RNA聚合酶在体外可通读前导基因和N基因之间的边界。
J Virol. 1981 May;38(2):792-6. doi: 10.1128/JVI.38.2.792-796.1981.
10
Structure and origin of a snapback defective interfering particle RNA of vesicular stomatitis virus.水疱性口炎病毒的一种回跳缺陷干扰颗粒RNA的结构与起源
J Virol. 1981 Feb;37(2):661-72. doi: 10.1128/JVI.37.2.661-672.1981.
Zotero 插件