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[联合放疗对宫颈癌患者促肾上腺皮质激素、皮质醇和醛固酮血水平的影响]

[The effect of combined radiotherapy on blood levels of ACTH, cortisol and aldosterone in cervical cancer].

作者信息

Modnikov O P

出版信息

Vopr Onkol. 1984;30(3):37-40.

PMID:6324489
Abstract

Blood-ACTH, cortisol and aldosterone levels in patients with cancer of the uterine cervix were measured radioimmunologically prior to complex radiotherapy, following a half-dose exposure of tumor focus and immediately on completion of the treatment course. Patients showed a rise in cortisol and aldosterone levels and a slight increase in ACTH. Radiation therapy inhibited production of cortisol and aldosterone matched by a rise in ACTH output.

摘要

采用放射免疫法测定了子宫颈癌患者在综合放射治疗前、肿瘤病灶半量照射后以及疗程结束即刻的血促肾上腺皮质激素（ACTH）、皮质醇和醛固酮水平。患者的皮质醇和醛固酮水平升高，ACTH略有增加。放射治疗抑制了皮质醇和醛固酮的产生，同时ACTH分泌增加。

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