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右旋苯丙胺和安慰剂对多动症儿童选择性注意力的练习效应。

Dextroamphetamine and placebo practice effects on selective attention in hyperactive children.

作者信息

Fisher M A

出版信息

J Abnorm Child Psychol. 1978 Mar;6(1):25-32. doi: 10.1007/BF00915779.

DOI:10.1007/BF00915779
PMID:632457
Abstract

Three groups of boys referred to a hospital study unit for evaluation of hyperactive behavior were tested on a classification task involving selective attention while on either dextroamphetamine (D) or placebo (P). In two sessions, groups had D first, P second (DP), or PD, or PP. Amphetamine reduces a response times in general and reduces interference due to orthogonally varying irrelevant information. Practice while on placebo improves performance in a subsequent placebo session. Practice while on amphetamine does not, however, improve performance in the subsequent session on placebo. Assessment of the extent of the drug-state-related practice effect is necessary for evaluation of long-term benefits of dextroamphetamine therapy in these children.

摘要

三组因多动行为被转介到医院研究单位进行评估的男孩,在一项涉及选择性注意力的分类任务中接受测试,测试时他们分别服用右旋苯丙胺(D)或安慰剂(P)。在两个疗程中,这些组分别先服用D,后服用P(DP),或先服用P,后服用D(PD),或两次都服用P(PP)。一般来说,苯丙胺会缩短反应时间,并减少因正交变化的无关信息而产生的干扰。在服用安慰剂时进行练习会提高随后安慰剂疗程中的表现。然而,在服用苯丙胺时进行练习并不会提高随后安慰剂疗程中的表现。评估与药物状态相关的练习效果程度对于评估右旋苯丙胺疗法对这些儿童的长期益处是必要的。

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本文引用的文献

1
Stimulant-related state-dependent learning in hyperactive children.多动症儿童中与兴奋剂相关的状态依存性学习
Science. 1976 Jun 25;192(4246):1354-7. doi: 10.1126/science.1273596.
2
Conners' Teacher Rating Scale for use in drug studies with children--an empirical study.用于儿童药物研究的康纳斯教师评定量表——一项实证研究。
J Abnorm Child Psychol. 1975;3(3):217-29. doi: 10.1007/BF00916752.
3
Selective attention and the processing of integral and nonintegral dimensions: a development study.
J Exp Child Psychol. 1976 Aug;22(1):73-85. doi: 10.1016/0022-0965(76)90091-6.