Rapoport J L, Tepsic P N, Grice J, Johnson C, Langer D
Psychiatry Res. 1980 Jul;2(3):225-9. doi: 10.1016/0165-1781(80)90014-1.
The motor activity of 10 hyperactive boys was measured during eight 1-hour active gym classes. Children received either dextroaomphetamine (0.5 mg/kg) or placebo elixir before each class, in a double-blind design. The program for each of the classes was participation in the active sports: hockey, basketball, and/or roller skating; the "task" throughout each hour was to play vigorously and continuously. The boys' mean hourly activity following amphetamine was slightly but significantly less than that following placebo. This finding is contradictory to the hypothesis that improved attention to an active task on stimulant would result in increased motor activity, and suggests the possibility of an independent direct effect of amphetamine on the motor system.
在八节为时1小时的活跃体育课期间，对10名多动男孩的运动活动进行了测量。采用双盲设计，孩子们在每节课前服用右旋苯丙胺（0.5毫克/千克）或安慰剂酏剂。每节课的活动安排是参与活跃的体育运动：曲棍球、篮球和/或轮滑；每个小时的“任务”是持续积极地玩耍。服用苯丙胺后男孩的平均每小时活动量略低于但显著低于服用安慰剂后的活动量。这一发现与兴奋剂能提高对活跃任务的注意力从而导致运动活动增加的假设相矛盾，并表明苯丙胺可能对运动系统有独立的直接作用。
