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α-促黑素和β-内啡肽样免疫反应存在于大鼠十二指肠的神经元和神经纤维内。

alpha-melanotropin and beta-endorphin-like immunoreactivities are contained within neurons and nerve fibers of the rat duodenum.

作者信息

Wolter H J

出版信息

Brain Res. 1984 Mar 19;295(2):378-84. doi: 10.1016/0006-8993(84)90991-0.

DOI:10.1016/0006-8993(84)90991-0
PMID:6324951
Abstract

Both alpha-melanotropin and beta-endorphin were revealed by immunofluorescence microscopy studies within neurons and nerve fibers of the rat duodenum. An immunohistochemical staining for alpha-melanotropin was seen within neuronal cell bodies and nerve fibers bundles of the myenteric and submucous plexus. A beta-endorphin immunofluorescence was visualized within perikarya and nerve fibers of both the myenteric and submucous plexus. alpha-Melanotropin as well as beta-endorphin immunoreactivities were strictly localized to structures of the enteric nervous system. In crypts and epithelial cells only a non-specific staining was observed.

摘要

通过免疫荧光显微镜研究发现,α-促黑素和β-内啡肽存在于大鼠十二指肠的神经元和神经纤维中。在肌间神经丛和黏膜下神经丛的神经元细胞体和神经纤维束中可见α-促黑素的免疫组织化学染色。在肌间神经丛和黏膜下神经丛的核周体和神经纤维中均可见β-内啡肽免疫荧光。α-促黑素以及β-内啡肽免疫反应性严格定位于肠神经系统的结构中。在肠隐窝和上皮细胞中仅观察到非特异性染色。

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1
alpha-melanotropin and beta-endorphin-like immunoreactivities are contained within neurons and nerve fibers of the rat duodenum.α-促黑素和β-内啡肽样免疫反应存在于大鼠十二指肠的神经元和神经纤维内。
Brain Res. 1984 Mar 19;295(2):378-84. doi: 10.1016/0006-8993(84)90991-0.
2
alpha-Melanotropin, beta-endorphin and adrenocorticotropin-like immunoreactivities are colocalized within duodenal myenteric plexus perikarya.
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Adrenocorticotropin and beta-endorphin are colocalized in the nervous system of rat duodenum.
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gamma-Melanotropin is contained within neurons, nerve fibres and nerve endings of rat duodenum.
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Co-existence of the enkephalinergic system and the melanotropinergic system in the rat duodenum shown by immunohistochemistry.
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Corticotropin-releasing factor is contained within perikarya and nerve fibres of rat duodenum.
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Dynorphin-A (1-8) is contained within perikarya, nerve fibres and nerve terminals of rat duodenum.
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Ultrastructural evidence for beta-endorphin-like immunoreactivity in the nervous system of the rat duodenum.
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Corticotropin-releasing factor: immunohistochemical colocalization with adrenocorticotropin and beta-endorphin, but not with Met-enkephalin, in subpopulations of duodenal perikarya of rat.促肾上腺皮质激素释放因子:在大鼠十二指肠周核亚群中与促肾上腺皮质激素和β-内啡肽存在免疫组织化学共定位,但与甲硫氨酸脑啡肽不存在共定位。
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