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对切开的枪乌贼巨大轴突中钠电流波动的分析。

Analysis of sodium current fluctuations in the cut-open squid giant axon.

作者信息

Llano I, Bezanilla F

出版信息

J Gen Physiol. 1984 Feb;83(2):133-42. doi: 10.1085/jgp.83.2.133.

Abstract

Patch pipettes were used to record the current arising from small populations of sodium channels in voltage-clamped cut-open squid axons. The current fluctuations associated with the time-variant sodium conductance were analyzed with nonstationary statistical techniques in order to obtain an estimate for the conductance of a single sodium channel. The results presented support the notion that the open sodium channel in the squid axon has only one value of conductance, 3.5 pS.

摘要

膜片吸管被用于记录电压钳制的切断鱿鱼轴突中少量钠通道产生的电流。利用非平稳统计技术分析与时变钠电导相关的电流波动,以便获得单个钠通道电导的估计值。所呈现的结果支持这样一种观点,即鱿鱼轴突中的开放钠通道只有一个电导值,即3.5皮西门子。

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本文引用的文献

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Sodium and calcium channels in bovine chromaffin cells.牛嗜铬细胞中的钠通道和钙通道。
J Physiol. 1982 Oct;331:599-635. doi: 10.1113/jphysiol.1982.sp014394.
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Modification of single Na+ channels by batrachotoxin.由蟾毒素对单个钠离子通道的修饰作用。
Proc Natl Acad Sci U S A. 1982 Nov;79(21):6732-6. doi: 10.1073/pnas.79.21.6732.
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