Payne J, Koopmann C F
Laryngoscope. 1984 May;94(5 Pt 1):608-11.
A patient is described who was evaluated for persistent hoarseness. Although an initial diagnosis of squamous cell carcinoma of the larynx was made, review of the pathology slides revealed pseudoepitheliomatous hyperplasia, acanthosis, and what appeared to be a fungal infection. After a detailed work-up was initiated the patient was treated successfully with ketoconazole for a blastomycosis infection of the larynx. The literature relative to blastomycosis infections of the respiratory larynx is reviewed. The authors emphasize that patients who show evidence of acanthosis and pseudoepitheliomatous hyperplasia along with the diagnosis of squamous cell carcinoma should be suspected as having a potential fungal infection.
本文描述了一名因持续性声音嘶哑接受评估的患者。尽管最初诊断为喉鳞状细胞癌，但病理切片复查显示为假上皮瘤样增生、棘皮症以及疑似真菌感染。在开始进行详细检查后，患者接受酮康唑治疗，成功治愈了喉部芽生菌病感染。本文回顾了有关呼吸道喉部芽生菌病感染的文献。作者强调，对于诊断为鳞状细胞癌且伴有棘皮症和假上皮瘤样增生迹象的患者，应怀疑可能存在真菌感染。
