[Inhibitory responses of neurons of an isolated strip of auditory cortex to intracortical stimulation in the cat].

Neuronal reactions to intracortical stimulation at a depth of 1.2-1.4 mm have been investigated in an acutely isolated auditory cortex slab from the cat brain (A-1). It is shown that among neuronal reactions to such stimulation primary inhibitory postsynaptical potentials (IPSPs) prevailed. Latent periods of the inhibitory reactions did not exceed 10 ms. Amplitude and duration of IPSPs did not differ from those of inhibitory responses of neurons in the intact auditory cortex. Some peculiarities in the development of inhibitory responses were found in different layers. The distribution of neurons reacting by IPSP was analyzed according to the slab depth, the duration of primary IPSPs and their latent periods, depending on the distance between the recording microelectrode and stimulating electrode. The mechanisms of inhibitory process spreading in an isolated slab and the mechanisms providing prolongation of cortical inhibitory responses are discussed.