Bevan J A, Bevan R D
Blood Vessels. 1984;21(3):110-6.
There are patterns in the distribution of the characteristics of vascular alpha-adrenoceptors. Sudden changes in their mechanism occur at particularly sites along the main branches of the aorta; in some regional vascular beds, but not others, there is a progressive reduction in the response that can be elicited through the alpha-adrenoceptor; in smaller blood vessels, alpha- and beta-adrenoceptors may be spatially separated in the vessel wall; in most blood vessels, the inner smooth muscle is more sensitive to alpha-agonists and more dependent on sequestered calcium than the outer. There is little support for a significant physiological role of the proposed gamma-receptor.
血管α-肾上腺素能受体的特性分布存在规律。其机制的突然变化发生在主动脉主要分支的特定部位；在一些区域血管床，而非其他区域，通过α-肾上腺素能受体引发的反应会逐渐减弱；在较小的血管中，α-和β-肾上腺素能受体可能在血管壁上在空间上相互分离；在大多数血管中，内层平滑肌对α-激动剂更敏感，且比外层更依赖于储存的钙。关于所提出的γ-受体的重要生理作用，几乎没有证据支持。
