Crespi F, Jouvet M
Brain Res. 1984 May 7;299(1):113-9. doi: 10.1016/0006-8993(84)90793-5.
Nuclei raphe dorsalis ( RDN ), centralis (RCN), pontis (RPN) and magnus ( RMN ) were separately studied using differential pulse voltammetry ( DPV ) in chronic freely moving rats during the recording of their sleep-waking cycle by polygraphic technique. In each of these nuclei the height of the electrochemical signal appearing at +300 mV (peak 3) was maximum during waking (W), lower during slow-wave sleep (SWS) and minimum during paradoxical sleep (PS). Some pharmacological treatments indicated that in each of these nuclei the peak 3 represents the oxidation of the 5-hydroxyindoles. DPV measurements performed during specific behavioral states (eating, grooming, washing, drinking) called active waking (AW) or manipulations (handling, tail-pinch) demonstrated that this technique enables detection of changes occurring in animals under physiological conditions.
在通过多导记录技术记录慢性自由活动大鼠睡眠-觉醒周期的过程中，使用差分脉冲伏安法（DPV）分别研究了背侧中缝核（RDN）、中央中缝核（RCN）、脑桥中缝核（RPN）和大细胞中缝核（RMN）。在这些核团中的每一个中，出现在+300 mV（峰3）处的电化学信号高度在清醒（W）时最大，在慢波睡眠（SWS）时较低，在异相睡眠（PS）时最小。一些药理学处理表明，在这些核团中的每一个中，峰3代表5-羟吲哚的氧化。在称为主动清醒（AW）的特定行为状态（进食、梳理、清洗、饮水）或操作（处理、夹尾）期间进行的DPV测量表明，该技术能够检测动物在生理条件下发生的变化。
