Small D G, Matthews W B, Small M
J Neurol Sci. 1978 Feb;35(2-3):211-24. doi: 10.1016/0022-510x(78)90004-7.
Abnormalities of the potential evoked by stimulation of the median nerve and recorded over the cervical spine were found in 59% of patients with multiple sclerosis (MS) this proportion increasing to 69% of those in the definite diagnosis category and to 100% in the severely disabled. Abnormalities were often found in the absence of relevant clinical signs and the method appears to be capable of revealing clinically silent plaques. In patients with a single episode of neurological disease, including retrobulbar neuritis, and at least compatible with the onset of MS, the proportion of abnormalities did not rise above 18%. Only prolonged follow-up will permit assessment of the value of this and other evoked potential techniques in the detection of the early case of the disease.
在59%的多发性硬化症（MS）患者中，发现刺激正中神经并在颈椎记录到的诱发电位异常，这一比例在明确诊断的患者中增至69%，在严重残疾患者中则达到100%。异常情况常常在没有相关临床体征时就被发现，该方法似乎能够揭示临床上无症状的斑块。在患有单次神经系统疾病（包括球后视神经炎）且至少与MS发病相符的患者中，异常比例未超过18%。只有通过长期随访才能评估这种及其他诱发电位技术在早期疾病检测中的价值。
