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酒精性神经病变中孤立神经纤维的定量研究(作者译)

[Quantitative study of isolated nerve fibers in alcoholic neuropathy (author's transl)].

作者信息

Said G, Landrieu P

出版信息

J Neurol Sci. 1978 Feb;35(2-3):317-30. doi: 10.1016/0022-510x(78)90012-6.

Abstract

This is a report of qualitative and quantitative study of nerve fibres in alcoholic neuropathy. In order to determine the frequency of segmental demyelination in alcoholic neuropathy, 10 nerve biopsies from 9 patients were studied by teasing; 100 consecutive fibres were isolated from each nerve and classified according to their morphology. This study confirms that segmental demyelination is a rare finding in this condition. Segmental demyelination of peripheral nerve fibres occurred in three cases and affected 6 to 8 per cent of the fibres. Wallerian degeneration of nerve fibres was found in all ten nerve biopsy specimens and affected 31 to 98 percent of the isolated fibres.

摘要

这是一篇关于酒精性神经病变中神经纤维的定性和定量研究报告。为了确定酒精性神经病变中节段性脱髓鞘的发生率,对9例患者的10份神经活检样本进行了分离研究;从每条神经中分离出100根连续的纤维,并根据其形态进行分类。该研究证实,节段性脱髓鞘在这种情况下是一种罕见的发现。周围神经纤维的节段性脱髓鞘发生在3例患者中,受累纤维占6%至8%。在所有10份神经活检样本中均发现了神经纤维的瓦勒变性,受累分离纤维占31%至98%。

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