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第三代头孢菌素头孢哌酮和头孢噻肟的使用经验:报告

Experience with the third generation cephalosporins, cefoperazone and cefotaxime: report.

作者信息

Reddy J

出版信息

N Z Med J. 1984 May 9;97(755):293-6.

PMID:6328390
Abstract

The efficacy of the third generation cephalosporins, ceforperazone and cefotaxime, was evaluated in a provincial hospital in a small group of patients with severe infections. In one study, patients with severe sepsis were randomly allocated to a group receiving either cefoperazone or ampicillin (ticarcillin or cloxacillin) and gentamicin. In the other trial, a selected group of ill patients was given cefotaxime. Clinical and laboratory analyses showed that these two drugs are safe, well tolerated and effective in the blind treatment of severe infections.

摘要

在一家省级医院,对一小群重症感染患者评估了第三代头孢菌素头孢哌酮和头孢噻肟的疗效。在一项研究中,严重脓毒症患者被随机分配到接受头孢哌酮或氨苄西林(替卡西林或氯唑西林)加庆大霉素治疗的组。在另一项试验中,一组选定的患病患者接受了头孢噻肟治疗。临床和实验室分析表明,这两种药物在重症感染的盲法治疗中安全、耐受性良好且有效。

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