• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一种灭活马疱疹病毒1型疫苗的试验:用1型病毒进行攻毒

Trials of an inactivated equid herpesvirus 1 vaccine: challenge with a subtype 1 virus.

作者信息

Burrows R, Goodridge D, Denyer M S

出版信息

Vet Rec. 1984 Apr 14;114(15):369-74. doi: 10.1136/vr.114.15.369.

DOI:10.1136/vr.114.15.369
PMID:6328728
Abstract

Vaccinated yearlings , two-year-old and in-foal pony mares with appropriate controls were exposed to aerosols of a subtype 1 virus one to two months after two or three vaccinations; all became infected. No obvious differences in the febrile responses, clinical signs and subsequent abortions were found between vaccinated and control mares. All vaccinated yearlings and two-year-old ponies developed a febrile respiratory disease but this was less severe than that suffered by the controls and the amounts and duration of virus shedding were reduced.

摘要

接种疫苗的一岁马、两岁马和怀孕母马及其相应对照,在进行两到三次疫苗接种后的一到两个月,暴露于1型病毒的气溶胶中;所有马匹均被感染。接种疫苗的母马和对照母马在发热反应、临床症状及随后的流产情况方面未发现明显差异。所有接种疫苗的一岁马和两岁马都出现了发热性呼吸道疾病,但症状比对照马轻,病毒排出量和持续时间也有所减少。

相似文献

1
Trials of an inactivated equid herpesvirus 1 vaccine: challenge with a subtype 1 virus.一种灭活马疱疹病毒1型疫苗的试验:用1型病毒进行攻毒
Vet Rec. 1984 Apr 14;114(15):369-74. doi: 10.1136/vr.114.15.369.
2
Viraemia and abortions are not prevented by two commercial equine herpesvirus-1 vaccines after experimental challenge of horses.在对马匹进行实验性攻毒后,两种市售的马疱疹病毒1型疫苗无法预防病毒血症和流产。
Vet Q. 1990 Apr;12(2):80-6. doi: 10.1080/01652176.1990.9694249.
3
Trials of an inactivated equid herpesvirus 1 vaccine: challenge with a subtype 2 virus.
Vet Rec. 1984 Apr 14;114(15):375-81. doi: 10.1136/vr.114.15.375.
4
Derivation and characterisation of a live equid herpes virus-1 (EHV-1) vaccine to protect against abortion and respiratory disease due to EHV-1.一种用于预防马疱疹病毒1型(EHV-1)引起的流产和呼吸道疾病的活EHV-1疫苗的衍生与特性研究
Vet Microbiol. 2003 Jan 2;91(1):23-39. doi: 10.1016/s0378-1135(02)00259-6.
5
Application of a chemically inactivated, adjuvanted vaccine to control abortigenic infection of mares by equine herpesvirus I.应用化学灭活佐剂疫苗控制马疱疹病毒I引起的母马流产感染。
Dev Biol Stand. 1982;52:493-8.
6
Clinical and virological evaluation of the efficacy of an inactivated EHV1 and EHV4 whole virus vaccine (Duvaxyn EHV1,4). Vaccination/challenge experiments in foals and pregnant mares.一种灭活的EHV1和EHV4全病毒疫苗(Duvaxyn EHV1,4)疗效的临床和病毒学评估。驹和怀孕母马的疫苗接种/攻毒实验。
Vaccine. 2001 Jul 20;19(30):4307-17. doi: 10.1016/s0264-410x(01)00131-1.
7
Serological responses and clinical outcome after vaccination of mares and foals with equine herpesvirus type 1 and 4 (EHV-1 and EHV-4) vaccines.马和驹接种马疱疹病毒 1 型和 4 型(EHV-1 和 EHV-4)疫苗后的血清学反应和临床结果。
Vet Microbiol. 2012 Nov 9;160(1-2):9-16. doi: 10.1016/j.vetmic.2012.04.042. Epub 2012 May 8.
8
Vaccines for EHV1 abortion.
Vet Rec. 1983 Mar 19;112(12):285. doi: 10.1136/vr.112.12.285-a.
9
Equine herpesvirus.马疱疹病毒
Vet Rec. 1989 May 13;124(19):519. doi: 10.1136/vr.124.19.519-a.
10
Equine herpesvirus 1 infection in mares vaccinated with a live-virus rhinopneumonitis vaccine attenuated in cell culture.用在细胞培养中减毒的活病毒鼻肺炎疫苗接种母马后发生的马疱疹病毒1型感染。
Can Vet J. 1979 May;20(5):145-7.

引用本文的文献

1
Viremia and nasal shedding for the diagnosis of equine herpesvirus-1 infection in domesticated horses.病毒血症和鼻分泌物用于诊断家养马的马疱疹病毒-1 感染。
J Vet Intern Med. 2024 May-Jun;38(3):1765-1791. doi: 10.1111/jvim.16958. Epub 2023 Dec 9.
2
Vaccination for the prevention of equine herpesvirus-1 disease in domesticated horses: A systematic review and meta-analysis.马疱疹病毒 1 病在驯养马中的预防接种:系统评价和荟萃分析。
J Vet Intern Med. 2024 May-Jun;38(3):1858-1871. doi: 10.1111/jvim.16895. Epub 2023 Nov 6.
3
Primary vaccination in foals: a comparison of the serological response to equine influenza and equine herpesvirus vaccines administered concurrently or 2 weeks apart.
马驹的初次免疫接种:同时或相隔 2 周接种马流感和马疱疹病毒疫苗的血清学反应比较。
Arch Virol. 2021 Feb;166(2):571-579. doi: 10.1007/s00705-020-04846-6. Epub 2021 Jan 7.
4
Aetiology of Canine Infectious Respiratory Disease Complex and Prevalence of its Pathogens in Europe.犬传染性呼吸道疾病综合征的病因及其病原体在欧洲的流行情况
J Comp Pathol. 2020 Apr;176:86-108. doi: 10.1016/j.jcpa.2020.02.005. Epub 2020 Mar 17.
5
Intranasal treatment with CpG-B oligodeoxynucleotides protects CBA mice from lethal equine herpesvirus 1 challenge by an innate immune response.鼻腔内给予 CpG-B 寡脱氧核苷酸通过先天免疫反应保护 CBA 小鼠免受致死性马疱疹病毒 1 的攻击。
Antiviral Res. 2019 Sep;169:104546. doi: 10.1016/j.antiviral.2019.104546. Epub 2019 Jun 25.
6
Immunization with Attenuated Equine Herpesvirus 1 Strain KyA Induces Innate Immune Responses That Protect Mice from Lethal Challenge.用减毒马疱疹病毒1型KyA株免疫可诱导先天免疫反应,保护小鼠免受致死性攻击。
J Virol. 2016 Aug 26;90(18):8090-104. doi: 10.1128/JVI.00986-16. Print 2016 Sep 15.
7
Expression of the full-length form of gp2 of equine herpesvirus 1 (EHV-1) completely restores respiratory virulence to the attenuated EHV-1 strain KyA in CBA mice.马疱疹病毒1型(EHV-1)全长形式的gp2在CBA小鼠中可使减毒的EHV-1毒株KyA的呼吸道毒力完全恢复。
J Virol. 2005 Apr;79(8):5105-15. doi: 10.1128/JVI.79.8.5105-5115.2005.
8
Severe murine lung immunopathology elicited by the pathogenic equine herpesvirus 1 strain RacL11 correlates with early production of macrophage inflammatory proteins 1alpha, 1beta, and 2 and tumor necrosis factor alpha.致病性马疱疹病毒1型毒株RacL11引发的严重小鼠肺部免疫病理学与巨噬细胞炎性蛋白1α、1β和2以及肿瘤坏死因子α的早期产生相关。
J Virol. 2000 Nov;74(21):10034-40. doi: 10.1128/jvi.74.21.10034-10040.2000.
9
In situ study on the pathogenesis and immune reaction of equine herpesvirus type 1 (EHV-1) infections in mice.马疱疹病毒1型(EHV-1)感染小鼠的发病机制和免疫反应的原位研究
Immunology. 1998 Mar;93(3):329-34. doi: 10.1046/j.1365-2567.1998.00451.x.
10
Characterization of the cytolytic T-lymphocyte response to a candidate vaccine strain of equine herpesvirus 1 in CBA mice.CBA小鼠对马疱疹病毒1型候选疫苗株的细胞溶解性T淋巴细胞反应的特性分析
J Virol. 1998 Jul;72(7):5366-72. doi: 10.1128/JVI.72.7.5366-5372.1998.