Warren S, Schreiber J R, Epstein M F
Am J Dis Child. 1984 Jul;138(7):686-8. doi: 10.1001/archpedi.1984.02140450068021.
Two newborns had necrotizing enterocolitis (NEC) and severe hemolytic anemia. Clostridium perfringens was identified in the peritoneal fluid of both infants, supporting the previous association of C perfringens with hemolysis reported in adult patients. Infants with NEC and hemolytic anemia should be aggressively treated with surgical debridement and high-dose parenteral penicillin G potassium. Similarly, Gram's stain of peritoneal fluid and resected bowel at laparotomy for NEC may be useful for early identification of the primary organism.
两名新生儿患有坏死性小肠结肠炎（NEC）和严重溶血性贫血。在两名婴儿的腹腔积液中均发现了产气荚膜梭菌，这支持了先前报道的产气荚膜梭菌与成年患者溶血之间的关联。患有NEC和溶血性贫血的婴儿应积极接受手术清创和大剂量静脉注射青霉素G钾治疗。同样，在因NEC进行剖腹手术时，对腹腔积液和切除的肠段进行革兰氏染色可能有助于早期识别主要病原体。
