新生儿坏死性小肠结肠炎中的梭菌毒素
Clostridial toxins in neonatal necrotising enterocolitis.
作者信息
Thomas D F, Fernie D S, Bayston R, Spitz L
出版信息
Arch Dis Child. 1984 Mar;59(3):270-2. doi: 10.1136/adc.59.3.270.
Abstract
Clostridium difficile cytopathic toxin was found in the faeces or gut content of five of 39 neonates with necrotising enterocolitis (NEC). Toxin concentrations were uniformly low and did not differ from those found in healthy neonates. C difficile is unlikely to be involved in the pathogenesis of NEC. Stools from 33 babies with NEC were also tested for C perfringens alpha toxin, with negative results.
摘要
在39例患有坏死性小肠结肠炎（NEC）的新生儿中，有5例的粪便或肠道内容物中发现了艰难梭菌细胞病变毒素。毒素浓度均较低，与健康新生儿的毒素浓度无差异。艰难梭菌不太可能参与NEC的发病机制。对33例患有NEC的婴儿的粪便也进行了产气荚膜梭菌α毒素检测，结果为阴性。
相似文献
1
Clostridial toxins in neonatal necrotising enterocolitis.新生儿坏死性小肠结肠炎中的梭菌毒素
Arch Dis Child. 1984 Mar;59(3):270-2. doi: 10.1136/adc.59.3.270.
2
Pseudomembranous enterocolitis and the aetiological role of Clostridium difficile. An overview of the recent literature.伪膜性小肠结肠炎及艰难梭菌的病因学作用。近期文献综述。
S Afr Med J. 1981 Oct 17;60(16):623-5.
3
Clindamycin-induced enterocolitis in hamsters as a model of pseudomembranous colitis in patients.以仓鼠克林霉素诱导的小肠结肠炎作为患者伪膜性结肠炎的模型。
Infect Immun. 1978 May;20(2):526-9. doi: 10.1128/iai.20.2.526-529.1978.
4
Clostridium difficile isolation in neonates in a special care unit. Lack of correlation with necrotizing enterocolitis.特殊护理病房中新生儿艰难梭菌的分离。与坏死性小肠结肠炎无相关性。
Scand J Gastroenterol. 1984 May;19(3):441-4.
5
Neonatal necrotizing enterocolitis associated with penicillin-resistant, toxigenic Clostridium butyricum.新生儿坏死性小肠结肠炎与耐青霉素、产毒素丁酸梭菌相关。
Pediatrics. 1980 Dec;66(6):928-31.
6
Detection of clostridial toxins in stools from children with diarrhoea.腹泻儿童粪便中梭菌毒素的检测
J Med Microbiol. 1986 Aug;22(1):29-31. doi: 10.1099/00222615-22-1-29.
7
Role of Clostridium difficile in antibiotic-associated pseudomembranous colitis.艰难梭菌在抗生素相关性假膜性结肠炎中的作用。
Gastroenterology. 1978 Nov;75(5):778-82.
8
Clostridium difficile toxin in faecal specimens of healthy children and children with diarrhoea.健康儿童和腹泻儿童粪便标本中的艰难梭菌毒素
Acta Paediatr Scand. 1982 Mar;71(2):275-8. doi: 10.1111/j.1651-2227.1982.tb09414.x.
9
Use of gas-liquid chromatography as a screening test for toxigenic Clostridium difficile in diarrhoeal stools.使用气液色谱法作为腹泻粪便中产毒艰难梭菌的筛查试验。
J Clin Pathol. 1983 Nov;36(11):1233-6. doi: 10.1136/jcp.36.11.1233.
10
Enteric colonization in sporadic neonatal necrotizing enterocolitis.
J Pediatr Gastroenterol Nutr. 1985 Aug;4(4):591-5. doi: 10.1097/00005176-198508000-00017.
引用本文的文献
1
Necrotizing enterocolitis of the neonate with Clostridium perfringens: diagnosis, clinical course, and role of alpha toxin.新生儿产气荚膜梭菌坏死性小肠结肠炎：诊断、临床过程及α毒素的作用
Eur J Pediatr. 2008 Aug;167(8):891-5. doi: 10.1007/s00431-007-0614-9. Epub 2007 Oct 20.
2
Serogrouping of Clostridium difficile strains by slide agglutination.通过玻片凝集法对艰难梭菌菌株进行血清分型。
J Clin Microbiol. 1985 Mar;21(3):323-7. doi: 10.1128/jcm.21.3.323-327.1985.
3
Comparison of serogrouping and polyacrylamide gel electrophoresis for typing Clostridium difficile.艰难梭菌血清分型与聚丙烯酰胺凝胶电泳分型的比较
J Clin Microbiol. 1986 Dec;24(6):991-4. doi: 10.1128/jcm.24.6.991-994.1986.
4
Necrotising enterocolitis.坏死性小肠结肠炎
J Hosp Infect. 1986 Jan;7(1):4-12. doi: 10.1016/0195-6701(86)90020-4.
本文引用的文献
1
Clostridia colonization and clostridial toxin in neonatal necrotizing enterocolitis.新生儿坏死性小肠结肠炎中的梭菌定植与梭菌毒素
J Pediatr. 1981 Feb;98(2):308-11. doi: 10.1016/s0022-3476(81)80667-1.
2
Bacterial toxin and neonatal necrotizing enterocolitis.细菌毒素与新生儿坏死性小肠结肠炎
J Pediatr. 1980 Jan;96(1):114-5. doi: 10.1016/s0022-3476(80)80345-3.
3
The prevalence of Clostridium difficile and toxin in a nursery population: a comparison between patients with necrotizing enterocolitis and an asymptomatic group.
J Pediatr. 1982 Mar;100(3):435-9. doi: 10.1016/s0022-3476(82)80455-1.
4
Clostridium difficile toxin in asymptomatic neonates.
J Pediatr. 1982 Mar;100(3):431-4. doi: 10.1016/s0022-3476(82)80454-x.
5
Association between Clostridium difficile and enterocolitis in Hirschsprung's disease.
Lancet. 1982 Jan 9;1(8263):78-9. doi: 10.1016/s0140-6736(82)90216-1.
6
Neonatal necrotizing enterocolitis: absence of enteric bacterial toxins.
N Engl J Med. 1978 Aug 24;299(8):424. doi: 10.1056/nejm197808242990814.
Zotero 插件