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在缺乏循环多形核白细胞的情况下镓-67在炎症中的定位

Localization of Ga-67 in inflammations in the absence of circulating polymorphonuclear leukocytes.

作者信息

Dhawan V M, Sziklas J J, Spencer R P

出版信息

J Nucl Med. 1978 Mar;19(3):292-4.

PMID:632907
Abstract

Two cases are reported in whom there were no circulating polymorphonuclear leukocytes, on peripheral blood smears, at the time when Ga-67 citrate studies were carried out. In both of these women, Ga-67 accumulated at sites of inflammation. This shows that nonpolymorphonuclear pathways are sufficient to deliver Ga-67 and to allow its accumulation. The possible roles of lymphocytes or of noncellular pathways (such as transferrin to tissue lactoferrin) are mentioned.

摘要

报告了两例病例,在进行枸橼酸镓-67研究时,外周血涂片显示循环中的多形核白细胞不存在。在这两名女性中,镓-67均在炎症部位聚集。这表明非多形核途径足以输送镓-67并使其聚集。文中提到了淋巴细胞或非细胞途径(如转铁蛋白向组织乳铁蛋白的转化)可能发挥的作用。

相似文献

1
Localization of Ga-67 in inflammations in the absence of circulating polymorphonuclear leukocytes.在缺乏循环多形核白细胞的情况下镓-67在炎症中的定位
J Nucl Med. 1978 Mar;19(3):292-4.
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Studies on gallium accumulation in inflammatory lesions: III. roles of polymorphonuclear leukocytes and bacterial.炎症病灶中镓蓄积的研究:III. 多形核白细胞和细菌的作用
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Ga-67 scintigraphy of ischiorectal fossa horseshoe abscess.坐骨直肠窝马蹄形脓肿的镓-67闪烁扫描术。
Clin Nucl Med. 1989 Jul;14(7):538-9. doi: 10.1097/00003072-198907000-00014.
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Distribution of leukocytes labeled with In-111 oxine in dogs with acute inflammatory lesions.铟-111 奥克辛标记的白细胞在患有急性炎症性病变犬中的分布。
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Lactoferrin: its role as a Ga-67-binding protein in polymorphonuclear leukocytes.乳铁蛋白:其作为一种在多形核白细胞中与镓-67结合的蛋白的作用。
J Nucl Med. 1981 Jan;22(1):32-7.
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The effects of deferoxamine mesylate on gallium-67 distribution in normal and abscess-bearing animals: concise communication.甲磺酸去铁胺对正常动物和有脓肿动物体内镓-67分布的影响:简要通讯
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Soft-tissue abscesses in a diabetic patient. Localization by gallium citrate Ga 67 scanning and sonography.糖尿病患者的软组织脓肿。通过枸橼酸镓Ga 67扫描和超声检查进行定位。
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Studies of the vivo uptake of Ga-67 by an experimental abscess: concise communication.实验性脓肿对镓 - 67 的体内摄取研究:简要通讯
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Studies on gallium accumulation in inflammatory lesions: I. Gallium uptake by human polymorphonuclear leukocytes.炎症病灶中镓蓄积的研究:I. 人多形核白细胞对镓的摄取
J Nucl Med. 1978 Jan;19(1):36-43.
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The association of Ga-67 and lactoferrin.镓-67与乳铁蛋白的关联。
J Nucl Med. 1977 Jul;18(7):713-7.

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EJNMMI Res. 2011 Aug 17;1(1):14. doi: 10.1186/2191-219X-1-14.
2
Gallium-67 citrate as an aid to the diagnosis of infection in hip surgery.
Int Orthop. 1982;6(3):163-9. doi: 10.1007/BF00267726.
3
Gallium-67 myocardial imaging for the detection of myocarditis in the acute phase of Kawasaki disease (mucocutaneous lymph node syndrome): the usefulness of single photon emission computed tomography.镓-67心肌显像用于检测川崎病(黏膜皮肤淋巴结综合征)急性期的心肌炎:单光子发射计算机断层扫描的效用
Br Heart J. 1987 Oct;58(4):385-92. doi: 10.1136/hrt.58.4.385.
4
The mechanism of the localization of 67gallium citrate in experimental abscesses.柠檬酸镓在实验性脓肿中的定位机制。
Eur J Nucl Med. 1979 Aug 1;4(4):271-5. doi: 10.1007/BF00304882.