Friedl P, Hoppe J, Schairer H U
Biochem Biophys Res Commun. 1984 Apr 30;120(2):527-33. doi: 10.1016/0006-291x(84)91286-5.
The effect of various point mutations in subunits a and and c of the E. coli ATP-synthase was characterized. In each of the mutants there was no F0-dependent H+-conduction, but still an ATPase-activity comparable to wildtype activities. In addition, the subunit b could be extracted from the mutant's F0 but not from the F0 of wildtype. The effects are interpreted as a change in the conformation of F0 caused by the different mutations.
对大肠杆菌ATP合酶亚基a、b和c中各种点突变的影响进行了表征。在每个突变体中，均不存在F0依赖性H+传导，但仍具有与野生型活性相当的ATP酶活性。此外，亚基b可从突变体的F0中提取出来，但不能从野生型的F0中提取。这些影响被解释为由不同突变导致的F0构象变化。
