Radionuclide imaging of primary renal-cell carcinoma by I-131-labeled antitumor antibody.
作者信息
Belitsky P, Ghose T, Aquino J, Norvell S T, Blair A H
出版信息
J Nucl Med. 1978 Apr;19(4):427-30.
PMID:632934
Abstract
A goat antibody against human renal-cell carcinoma reacted on immunofluorescence with renal-cell carcinomas from 20 patients, but not with normal adult human tissues, including kidney. After i.v. administration the I-131-linked antibody showed preferential tumor localization in six of seven patients with primary renal carcinoma. Labeled antitumor antibodies may have the specificity for tumor imaging that current radiopharmaceuticals lack.
摘要
相似文献
1
Radionuclide imaging of primary renal-cell carcinoma by I-131-labeled antitumor antibody.
J Nucl Med. 1978 Apr;19(4):427-30.
2
Radionuclide imaging of metastases from renal-cell carcinoma by 131I-labeled antitumor antibody.
Radiology. 1978 Feb;126(2):515-7. doi: 10.1148/126.2.515.
3
4
Production and characterization of xenogeneic antisera to a human renal cell carcinoma-associated antigen.人肾细胞癌相关抗原异种抗血清的制备与鉴定
J Natl Cancer Inst. 1979 Aug;63(2):301-8.
5
6
Tumor localization of 131-I-labeled antibodies by radionuclide inaging.通过放射性核素成像对¹³¹I标记抗体进行肿瘤定位
Radiology. 1975 Aug;116(02):445-8. doi: 10.1148/116.2.445.
8
Selective uptake of specifically purified antibodies to carcinoembryonic antigen of human adenocarcinoma.对人腺癌癌胚抗原特异性纯化抗体的选择性摄取。
Res Commun Chem Pathol Pharmacol. 1974 Dec;9(4):749-61.
9
Humoral cytotoxicity in human renal cell carcinoma.人肾细胞癌中的体液细胞毒性
Invest Urol. 1974 Mar;11(5):405-10.
引用本文的文献
1
Is there a role for radioimmunolocalization in diagnosis of intracranial malignancies?: discussion paper.放射免疫定位在颅内恶性肿瘤诊断中是否有作用？：讨论文件
J R Soc Med. 1984 Oct;77(10):847-54. doi: 10.1177/014107688407701010.
2
Scintigraphy and distribution of labeled antibodies in rats with tumors.肿瘤大鼠的闪烁扫描及标记抗体的分布
Eur J Nucl Med. 1982;7(1):28-34. doi: 10.1007/BF00275241.
3
Echinococcus granulosus: the potential use of specific radiolabelled antibodies in diagnosis by immunoscintigraphy.细粒棘球绦虫：特异性放射性标记抗体在免疫闪烁显像诊断中的潜在应用。
Clin Exp Immunol. 1990 May;80(2):225-31. doi: 10.1111/j.1365-2249.1990.tb05238.x.
Zotero 插件