Dickgiesser N, Kuntz P
Br J Vener Dis. 1984 Jun;60(3):154-6. doi: 10.1136/sti.60.3.154.
We measured the activity of rosoxacin, fosfomycin, cefotiam, and spectinomycin against 51 isolates of beta-lactamase producing Neisseria gonorrhoeae, all of which were susceptible to each drug at sufficient concentrations. The development of strains of penicillinase producing N gonorrhoeae (PPNG) which are resistant to spectinomycin can therefore be avoided, as there are alternative drugs.
我们测定了罗索沙星、磷霉素、头孢替安和大观霉素对51株产β-内酰胺酶淋病奈瑟菌的活性,所有这些菌株在足够浓度下对每种药物均敏感。因此,由于存在替代药物,可以避免产生对大观霉素耐药的产青霉素酶淋病奈瑟菌(PPNG)菌株。