Studies on vitamin D (calciferol) and its analogues. 13. 3-Deoxy-3alpha-methyl-1alpha-hydroxyvitamin D3, 3-deoxy-3alpha-methyl-1alpha,25-dihydroxyvitamin D3, and 1alpha-hydroxy-3-epivitamin D3. Analogues with conformationally biased a rings.
作者信息
Okamura W H, Mitra M N, Pirio M R, Mouriño A, Carey S C, Norman A W
出版信息
J Org Chem. 1978 Feb 17;43(4):574-80. doi: 10.1021/jo00398a011.
PMID:632961
Abstract
摘要
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1
Studies on vitamin D (calciferol) and its analogues. 13. 3-Deoxy-3alpha-methyl-1alpha-hydroxyvitamin D3, 3-deoxy-3alpha-methyl-1alpha,25-dihydroxyvitamin D3, and 1alpha-hydroxy-3-epivitamin D3. Analogues with conformationally biased a rings.维生素D（骨化醇）及其类似物的研究。13. 3-脱氧-3α-甲基-1α-羟基维生素D3、3-脱氧-3α-甲基-1α,25-二羟基维生素D3和1α-羟基-3-表维生素D3。具有构象偏向A环的类似物。
J Org Chem. 1978 Feb 17;43(4):574-80. doi: 10.1021/jo00398a011.
2
Studies on vitamin D (calciferol) and its analogues. 15. 24-Nor-1alpha,25-dihydroxyvitamin D3 and 24-nor-25-hydroxy-5,6-trans-vitamin D3.维生素D（钙化醇）及其类似物的研究。15. 24-去甲-1α,25-二羟基维生素D3和24-去甲-25-羟基-5,6-反式维生素D3。
J Med Chem. 1978 Oct;21(10):1025-9. doi: 10.1021/jm00208a005.
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Studies on vitamin D (calciferol) and its analogues. 10. Side-chain analogues of 25-hydroxyvitamin D3.维生素D（骨化醇）及其类似物的研究。10. 25-羟基维生素D3的侧链类似物。
J Med Chem. 1977 Jan;20(1):5-11. doi: 10.1021/jm00211a002.
4
Vitamin D: 3-deoxy-lalpha-hydroxyvitamin D3, biologically active analog of lalpha-dihydroxyvitamin D3.维生素D：3-脱氧-1α-羟基维生素D3，1α-二羟基维生素D3的生物活性类似物。
Science. 1975 Jun 6;188(4192):1013-5. doi: 10.1126/science.1145184.
5
The synthesis and activity in vitro of 25-masked 1alpha-hydroxylated vitamin D3 analogs.
Steroids. 1978 Nov;32(4):453-66. doi: 10.1016/0039-128x(78)90058-2.
6
Studies on the mode of action of calciferol. X. 24-Nor-25-hydroxyvitamin D3, an analog of 25-hydroxyvitamin D3 having "anti-vitamin" activity.维生素D的作用方式研究。X. 24-去甲-25-羟基维生素D3，一种具有“抗维生素”活性的25-羟基维生素D3类似物。
Biochem Biophys Res Commun. 1975 Nov 17;67(2):797-802. doi: 10.1016/0006-291x(75)90883-9.
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1 alpha-hydroxy-25-fluorovitamin D3: a potent analogue of 1 alpha,25-dihydroxyvitamin D3.1α-羟基-25-氟维生素D3：一种1α,25-二羟基维生素D3的强效类似物。
Biochemistry. 1978 Jun 13;17(12):2387-92. doi: 10.1021/bi00605a021.
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24-Nor-25-hydroxyvitamin D3. A specific antagonist of vitamin D3 action in the chick.24-去甲-25-羟基维生素D3。雏鸡体内维生素D3作用的特异性拮抗剂。
J Biol Chem. 1979 Nov 25;254(22):11450-6.
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Effect of 1alpha-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 on intestine and bone in glucocorticoid-treated patients.1α-羟维生素D3和1,25-二羟维生素D3对糖皮质激素治疗患者肠道及骨骼的影响
Clin Endocrinol (Oxf). 1977 Dec;7 Suppl:177s-181s. doi: 10.1111/j.1365-2265.1977.tb03379.x.
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