Rusthoven J J, Feld R, Tuffnell P G
J Infect. 1984 May;8(3):241-6. doi: 10.1016/s0163-4453(84)93979-3.
Invasive fungal disease continues to be a significant problem among immunocompromised patients. We report a case of systemic Rhodotorula infection in a patient with acute myelogenous leukaemia. Rhodotorula was isolated from bone marrow on two separate occasions despite initial treatment with amphotericin B. Liver computerised tomographic scan suggested liver abscesses, and yeasts were seen on biopsy. The patient survived after aggressive antifungal and antileukaemia treatment. Rhodotorula fungaemia has been occasionally associated with shock. As our case illustrates, Rhodoturola may be a cause of invasive fungal disease in the immunocompromised host but can be eradicated if treated aggressively.
侵袭性真菌病在免疫功能低下患者中仍然是一个重大问题。我们报告了一例急性髓系白血病患者发生系统性红酵母感染的病例。尽管最初使用两性霉素B进行治疗，但在两个不同时间从骨髓中分离出了红酵母。肝脏计算机断层扫描显示有肝脓肿，活检时发现了酵母。患者在积极的抗真菌和抗白血病治疗后存活。红酵母菌血症偶尔与休克有关。正如我们的病例所示，红酵母可能是免疫功能低下宿主侵袭性真菌病的一个病因，但如果积极治疗可以根除。
