Korinek J K, Guarda L A, Bolivar R, Stroehlein J R
Gastroenterology. 1983 Sep;85(3):732-4.
A 33-yr-old Puerto Rican women was hospitalized for chemotherapy and multiple antibiotic treatment for relapse of acute myelomonocytic leukemia. While she was already receiving amphotericin for suspected Aspergillus infection, she developed hepatomegaly and abnormal liver enzymes with high serum bilirubin. The blood cultures were negative. Percutaneous liver biopsy revealed granulomatous fungal hepatitis identified by cultures as Trichosporon cutaneum. In spite of the continued administration of amphotericin, with the addition of 5-fluorocytosine, Trichosporon was later cultured from her blood, and she succumbed to fungemia and polymicrobial sepsis.
一名33岁的波多黎各女性因急性粒单核细胞白血病复发而住院接受化疗和多种抗生素治疗。在她已经因疑似曲霉菌感染而接受两性霉素治疗时，出现了肝肿大、肝酶异常以及高血清胆红素。血培养结果为阴性。经皮肝活检显示为肉芽肿性真菌性肝炎，培养鉴定为皮状丝孢酵母。尽管持续给予两性霉素，并加用了5-氟胞嘧啶，但后来她的血液中培养出了丝孢酵母，最终死于真菌血症和多种微生物败血症。
